Antacid

Question 1

Aluminium hydroxide

Answer 1

Antacid
- heartburn, peptic ulcers, dyspepsia

Neutralise gastric acid secretion
- Constipation, nausea, headache

Question 2

magnesium hydroxide

Answer 2

Antacid
- heartburn, peptic ulcers, dyspepsia

Neutralise gastric acid secretion
- Diarrhoea, nausea, headache

Question 3

Alginates (e.g. Gaviscon)

Answer 3

Antacid, alginate
- Heartburn, Acid reflux
(common choice during pregnancy)

reacts with acid and produces a viscous jelly which floats of aqueous solutions, providing a barrier to reduce reflux.
- gi, nausea, headache

Question 4

Bismuth compounds

Answer 4

Antacid
- To protect or promote formation off mucosal layer

stimulates mucosal bicarbonate and prostagladin production
- nausea vomiting , blackening tongue and faeces

Question 5

Sucralfate

Answer 5

Antacid
- To protect or promote formation off mucosal layer

binds to proteins in ulcer base, forms protective barrier against bile acid and pepsin.
- dizzy, rash , nausea

Question 6

Misoprostol

Answer 6

Antacid
- Gastric ulcers, To protect or promote formation off mucosal layer

synthetic analogue of prostaglandin.
- diarrhoea, abdo cramps