Immunology Pharmacology

Question 1

Adrenal insufficiency and orthostatic hypertension

Answer 1

Mineralocorticoids

Question 2

RA, severe psoriasis (including arthritis), therapeutic abortion, ectopic pregnancy, crohns disease, dermatomyositis/polymyositis, lupus, ALL, trophoblastic neoplasms, CA (breast, head, neck, lung), T-cell lymphoma, osteosarcoma, and non-hodgkin lymphoma

Answer 2

Methotrexate

Question 3

RA–mild disease (safe in pregnancy), malaria, and lupus

Answer 3

Hydroxychloroquine

Question 4

RA–mild dz (sulfasalazine is safe in pregnancy), IBD (mesalamine is considered first line over sulfasalazine [5-ASA derivative] due to fewer adverse reactions secondary to sulfa), and reactive arthritis

Answer 4

Sulfasalazine/Mesalamine

Question 5

RA–if they cannot take methotrexate or as an add on to methotrexate

Answer 5

Leflunomide

Question 6

Prevents organ transplant rejection and keeps pts off of corticosteroids in multiple AI dz (RA, crohns, UC, lupus, MS, dermatomyositis/polymyositis, erythema multiforme, pemphigus vulgaris, and psoriasis)

Answer 6

Azathioprine

Question 7

UC, Crohns dz, RA (not first line), psoriatic arthritis (not first line), and ankylosing spondylitis)

Answer 7

Anti-TNF Drugs (Etanercept, Inflixumab, Adalimumab)

Question 8

Vasculitis, leukemia, lymphoma, breast CA, nephrotic syndrome, lupus nephritis, and multiple myeloma

Answer 8

Cyclophosphamide

Question 9

Prevents organ transplant rejection and keeps patients off corticosteroids in multiple autoimmune diseases (Hepatitis, lupus nephritis, myasthenia gravis, and psoriasis)

Answer 9

Mycophenolate

Question 10

Acute gout prophylaxis (never started during an acute gouty attack)

Answer 10

Allopurinol

Question 11

Acute gout prophylaxis when the patient cannot take allopurinol

Answer 11

Febuxostat