M14 - biochemistry of plaque Flashcards

1
Q

define synergistic interactions (beneficial)

A
  • enzymes secreted or released upon lysis can benefit more than one species
  • metabolic products can be beneficial to other species
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2
Q

describe quorum sensing

A

co-ordination of gene expression and developmental pathways

, triggered by sensing the environment including behavious/ amount of other bacteria

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3
Q

what is homofermentation?

A

bacteria produce one fermentation product

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4
Q

what is heterofermentation?

A

bacteria produce more than one fermentation product

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5
Q

what bacteria are involved in homolactic fermentation?

A

Streptococci + lactobacilli –> lactic acid

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6
Q

which bacteria are involved in heterolactic

A

lactobacilli –> lactic acid and ethanol

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7
Q

mixed acid?

A

GNABS –> Lactic, acetic, formic acids

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8
Q

which nitrogen source is available as a nutrient source?

A

salivary proteins/ glycoproteins as nutrient source

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9
Q

what does the production of ammonia do?

A

counters development of low pH

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10
Q

why are carbohydrates important?

A

Sucrose promotes Eps

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11
Q

what does bacteriocin do?

A

it is a substance released by one bacteria that kills another usually by inducing a metabolic block
- substance is normally a protein

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12
Q

what is the product of the degradation of sulphur- containing amino acids?

A

hydrogen sulphide
vibrios and actinomyces
fusobacterium

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13
Q

when are endotoxins such as Lipopolysaccharides released?

A

released on death of bacteria

- found on outer membranes of gram -ve cell walls

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14
Q

what are the biological effects of endotoxin such as bacteria?

A
  • fever
  • raise capillary permeability
  • elicit information
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15
Q

many plaque bacteria release endotoxins also such as

A

veillonella

bacteriodes

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16
Q

Give an example of a bacterial enzyme that breaks down human tissues and cells

A
  • specific proteinases (collagenases)

- polysaccharides (hyaluronidases)

17
Q

which bacteria produces collagenase?

A

bacteriodes, prevotella and porphyromonas

18
Q

which disease occurs from volatile sulphur compounds?

A
  • porphyromonas
  • prevotella
  • fusobacterium
  • treponema