Blood Pharmacology Flashcards
1
Q
Intrinsic pathway
Antithrombin II
PTT for monitoring
A
Heparin
2
Q
Heparin AE
A
Heparin induced thrombocytopenia
Osteoporosis
3
Q
good bioavailability
Factor Xa
A
LMW Heparin
4
Q
Extrinsic
Vit K dependent
A
Warfarin
5
Q
How do you monitor warfarin
A
PROTIME/INR
6
Q
Used for
VHD
DVT
Afib
A
warfarin
7
Q
Warfarin Side effects
A
teratogenic
Skin tissue necrosis
8
Q
Treatment for warfarin toxicity
A
Vit K, FFP
9
Q
Inhibits cylcogenase and thromboxane A2
A
Aspirin
10
Q
First line for ischemic stroke
A
Aspirin
11
Q
MC Side effect of aspirin
A
Gastric irritation due to dec prostaglaindin (gastric mucosa protection)
12
Q
Aspirin AE
A
REYES’ syndrome
fullminant hepatitis
13
Q
inhibits ADP binding to receptor
inhibits glypoprotein GPIIa/IIb
inhibits platelet aggregatio
A
Clopidogrel
14
Q
inhibits thombin
A
Dabigatran (pradaxa)
15
Q
Heparin toxicity antidote
A
Protamine
