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Pharma > Antiseizure > Flashcards

Antiseizure Flashcards

1
Q

PHENYTOIN stands for?

A 
P450
Hirsutism
ENlarged gums
Yellow skin
Tocolytic
Osteomalacia
Interferes Vit B12
Neuropathy
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2
Q

Blocks Na channels
GTC Seizures
Tigeminal Neuragla

A

Carbamazepine

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3
Q

Carbamazepine SE

A

Diplopia
ataxia
Teratogenic

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4
Q

Increases GABA A Action
Febrile Seizure
Firs line for pregnancy

A

Phenobarbital

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5
Q

Phenobarbital SE

A

Decrease RR

CNS depression

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6
Q 
Used for all types of seizures
CI in pregnancy
Inhibits Na Channels
Increases GABA concentration
Hepatotoxic
Inhibits P450
A

Valproic Acid

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7
Q

Things that causes seizures

and drugs that inhibits them

A

Na channel opens
Increased glutamate
Too little GABA
Too much Ca

Phenytoin
Valproic acid
Cabamazepine

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8
Q

CP450 inducers

A

Carbamazepine
Phenobarbital
Phenytoin
rifampin

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9
Q

CP450 Inhibitors

A

Amiodarone
Cimetidine
azole antifungals
ritonavir

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10
Q

Suicide inhibitors(irreversibly inhibit metabolizing enzyme

A 
PTU
Spinirolactone
allopurinol
fluroxene
secobarbital
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11
Q

VALPROATE stands for?

A 
Vomiting
Alopecia
Liver toxicity
Pancytopenia
Retention of fats
Oedema
Appetite increase
Tremors
Enzyme inducer
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12
Q

inhibits Ca+ influx

Causes SJS

A

Ehtosuxamide

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13
Q

Prevents CAD
Causes Wernickes korsakoff syndrome
Dilated cardiomyopathy

A

Ethanol

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14
Q

Fatal amount of Ethanol

A

400mg/L

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15
Q

Hobnail cells are found in?

A

End stage cirrhosis

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Pharma (17 decks)

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