Endocrinopathies Flashcards
Diabetes mellitus
Lack of insulin
High blood sugar, glucose in the urine
Diabetes insipidus
Lack of AVP
Water loss, low blood volume, dehydration
Nephrogenic
Kidneys not responding to AVP
Water loss, low blood volume, dehydration
Addison’s (primary)
Destruction of Adrenal cortex
Altered carbohydrate metabolism, salt losing syndrome
Addison’s (secondary)
Lack of ACTH
Altered carbohydrate metabolism
Cushing’s (primary)
Adrenal tumor (excess cortisol) Hyperglycemia, protein catabolism
Cushing’s (secondary)
Excess cortisol and ACTH
Hyperglycemia, protein catabolism
Infantile hypothyroidism
Lack of T3 and T4
Decreased mentation, no growth, decreased BMR
Adult hypothyroidism
Lack of T3 and T4
Decreased mentation, decreased BMR
Hyperthyroidism
Excess T3 and T4
Increased BMR, hyperexcitivity
Hypoparathyroidism
Lack of PTH
Low blood calcium
Hyperparathyroidism
Excess PTH (tumor) Elevated blood calcium
Pseudohypothyroidism
Lack of renal response to PTH
Lowered blood calcium
Testicular feminizing syndrom
Absent or defective androgen receptors
Genital tract feminization in male
Hyperaldosteronism
Increased aldosterone. Adrenocortical tumor
Sodium retention, lowered blood volume, hypertension