Devin • Staphylococcus and Related Gram-Positive Cocci Bacteria

Question 1

fomites

Answer 1

objects that can carry infectious agents

Question 2

Toxins

Answer 2

• exfoliative toxins A and B - split intercellular bridges in stratum granulosum of epidermis; desmoglein-1 (part of desmosomes)
• Enterotoxins (A-E, G-X) – superantigens

Question 3

Toxin Mediated Diseases

Answer 3

food poisoning, scalded skin syndrome, toxic shock syndrome

Question 4

Cutaneous Diseases

Answer 4

• carbuncles – cluster of boils
• Folliculitis – inflammation of hair follicles; pimple
• foruncles – infection at hair follicle
• impetigo, wound and surgery infections

Question 5

MRSA means

Answer 5

Methicillin resistant Staphylococcus aureus

Question 6

T/F… Staphylococcus and Related Gram-Positive Cocci Bacteria have a capsule and slime layer

Answer 6

true

*have both

Question 7

Peptidoglycan

Answer 7

• endotoxin-like activity

* innate immunity via TLR2

Question 8

Surface Proteins Bound to Peptidoglycan

Answer 8

• Staph Protein A – binds Fc regions if IgGs, IgG1, IgG2, IgG4
• coagulase proteins – clumping factor proteins A and B

Question 9

Pneumonia

Answer 9

MRSA responsible for severe necrotizing pneumonia with massive hemoptysis (coughing up blood), septic shock, and high mortality rate

Question 10

Staphylococcus epidermis is coagulase?

Answer 10

coagulase negative