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patho exam 3 > breast CA > Flashcards

breast CA Flashcards

1
Q

etiology of acute mastitis

A

staph or strep

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2
Q

entire breast edematous
excretory ducts with pus
mostly PMNs

A

acute mastitis

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3
Q

fibrous scars
nipple retraction
small lumps in breast
idiopathic

A

chronic mastitis

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4
Q

main 2 etiologies of fibrocystic changes of breast

A

hormones and increased age

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5
Q

signs and symptoms of fibrocystic changes of breast

A

palpable lumps in breast
affects both breasts
pain, nodularity, sensitivity to palpation

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6
Q

only fibrocystic change related to carcinoma

A

atypical epithelial hyperplasia

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7
Q

what two hormones cause cell proliferation in excretory ducts of breast relating to fibrocystic changes

A

progesterone and estrogen

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8
Q

what is MC benign breast tumor

A

fibroadenoma

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9
Q

serous or bloody discharge from nipple

A

intraductal papilloma

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10
Q

main etiology of fat necrosis

A

trauma

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11
Q

chalk-white debris

nodule of grey-white firm tissue

A

fat necrosis

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12
Q

blue-domed cyst

A

fibrocystic change of breast

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13
Q

RF of breast CA

A 
sex
age
genetics
hormones
other CA
race
premalignant fibrocystic changes and multiple intraductal papillomas
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14
Q

marked lymphocytic infiltrate

A

medullary carcinoma

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15
Q

large gray-blue lakes of mucin and small islands of neoplastic cells

A

colloid or mucinous carcinoma

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16
Q

true nipple retraction

A

paget’s disease of the breast

17
Q

main location of breast CA

A

upper outer quadrant

18
Q

most mets found where

A

axillary area

19
Q

enlargement due to unusual proliferation of excretory ducts

hormonal changes in puberty

A

gynecomastia

20
Q

invades more rapidly

excess estrogens

A

male breast CA

21
Q

which CA has desmoplastic reaction

A

invasive ductal carcinoma

22
Q

which CA is multifocal and bilateral

A

lobular carcinoma in SITU

23
Q

tumors firm and gritty

A

invasive ductal carcinoma

24
Q

tumor rubbery and poorly circumscribed

A

invasive lobular carcinoma

25
Q

single-file rows of tumor cells

targetoid pattern of arrangement

A

invasive lobular carcinoma

26
Q

clinical presentation of breast CA

A

skin dimpling
lymphedema
skin thickening
nipple retraction

27
Q

diagnostic tools for breast CA

A

mammography
FNA
breast biopsy

28
Q

stage I breast CA

A

tumor localized and small

29
Q

tumor more than 2.5 cm, but less than 5 cm in diameter

may be lymph node mets

A

stage II breast CA

30
Q

more than 5 cm tumor with or without lymph node spread

A

stage III breast CA

31
Q

tumor any size

associated with distant mets

A

stage IV breast CA

patho exam 3 (12 decks)

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