Chapter 14 Pharm Flashcards

1
Q
  1. What is Culture and Sensitivity?
A

A culture is a test to find germs (such as bacteria or a fungus) that can cause an infection. A sensitivity test checks to see what kind of medicine, such as an antibiotic, will work best to treat the illness or infection.

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2
Q
  1. What is MIC?
A

(Minimum Inhibitory concentration) lowest concentration of antimicrobial that prevents visible growth.

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3
Q
  1. What is MBC?
A

(Minimum Bactericidal concentration) lowest concentration of antimicrobial agent that prevents growth of an organism after 24 hours.

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4
Q
  1. What is Bacteriostatic?
A

Drug that inhibits grow but don’t kill bacteria

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5
Q
  1. What is Bacteriocidal?
A

Drug that kills bacteria

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6
Q
  1. What is Time dependent response?
A

Kill rate influence by the time of drug concentration above MIC

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7
Q
  1. What is concentration dependent response?
A

Kill rate increases proportional with drug concentration.

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8
Q
  1. What is Pencillins?
A

Several different classes, natural and synthetic.

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9
Q
  1. Pencillins are bactericidal what?
A

Pencillins are bactericidal, demonstrate time-dependent killing and can act synergistically with aminoglycosides against some bacteria.

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10
Q
  1. What is common side effect of Pencillins?
A

Hypersensitivity

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11
Q
  1. What is Penicillin names usually end in ?”
A

LIN

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12
Q
  1. What is Penicillinase-resistant Penicillins?
A
  1. Active against gram-positive cocci (Staph and Strep)

2. Routinely used in skin and Soft tissue infections.

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13
Q
  1. What is Cephalosporins presently?
A

4th generation have extended gram positive and negative coverage.

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14
Q
  1. What is Cephalosporins?
  2. Bacteriostatic
  3. Bactericidal
A
  1. Bactericidal
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15
Q
  1. What is Aminoglycosides?
  2. Bacteriostatic
  3. Bactericidal
A

Bactericidal

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16
Q
  1. What is Aminoglycosides treatment for?
A

Gram negative organisms

Used for treating ventilator acquired pneumonias

17
Q
  1. TOBI is what?
  2. Carbapenems
  3. Aminoglycoside
A

Aminoglycoside

18
Q
  1. What is Quinolones?
  2. Bacteriostatic
  3. Bactericidal
A

Bactericidal

19
Q
  1. What is Quinolones treatment for?
A

Upper and lower respiratory tract infections

20
Q
  1. What is Tetracyclines?
  2. Bacteriostatic
  3. Bactericidal
A

Bacteriostatic

21
Q
  1. What is Tetracyclines treatment?
A

Treats respiratory tract infections, sexual transmitted infections and infections (good for acne)

22
Q
  1. What is Tetracyclines side effects?
A

Bone growth and not used with children

23
Q
  1. What is Macrolides?
  2. Bacteriostatic
  3. Bactericidal
A

Bacteriostatic

24
Q
  1. What is Macrolides treatment?
A

Used in treatment of both gram positive and gram negative organisms

25
Q
  1. What is Trimethoprim-Sulfamethoxazole?
  2. Bacteriostatic
  3. Bactericidal
A

Bacteriostatic

26
Q
  1. What is Trimethoprim-Sulfamethoxazole treatment?
A

PCP in cystic fibrosis