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Anterior Segment Disease > Corneal Dystrophies > Flashcards

Corneal Dystrophies Flashcards

1
Q

General characteristics of corneal dystrophies

A

bilateral
genetic (AD)
not systemic
recurrent corneal erosions common

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2
Q

Signs of Epithelial Basement Membrane Dystrophy

EBMD

A

thickened basement membrane with deposits of fibrillary material between BM and Bowman’s layer
maps/ dots/ fingerprints
REE

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3
Q

Meesmann’s Epithelial Dystrophy

A

tiny epithelial cysts

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4
Q

Tx for EBMD

A

same as for Recurrent Epithelial Erosions

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5
Q

Tx of Meesmann’s Epithelial Dystrophy

A

lubricants

PTK

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6
Q

Reis-Bucklers’ Corneal Dystrophy

A

replacement of Bowman’s layer with CT bands

appears as subepithelial deposits that increase in density to form reticular pattern

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7
Q

Tx of Reis-Bucklers’ Corneal Dystrophy

A

laser keratectomy

keratoplasty

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8
Q

Lattice Corneal Dystrophy

A

amyloid plaques deposit in stroma and evolve to have a lattice appearance

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9
Q

Mx for Lattice Corneal Dystrophy

A

keratoplasty for opacification

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10
Q

Granular Corneal Dystrophy

A

hyaline deposits in stroma

resemble sugar granules that fuse causing corneal haze

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11
Q

Mx of Granular Corneal Dystrophy

A

keratoplasty for opacification

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12
Q

Macular Corneal Dystrophy

A

autosomal recessive
accumulation of glycosaminoglycans
poorly defined spots (macules) become hazy and affect full stroma

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13
Q

Mx of Macular Corneal Dystrophy

A

Penetrating keratoplasty

recurrence common

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14
Q

Schnyder (Crystalline) Corneal Dystrophy

A

disorder of lipid metabolism resulting in deposits of phospholids and cholesterol

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15
Q

Signs of Schnyder (Crystalline) Corneal Dystrophy

A

central haze- crystalline deposits

prominent corneal arcus

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16
Q

Tx of Schnyder (Crystalline) Corneal Dystrophy

A

laser keratectomy or keratoplasty

17
Q

Fuchs’ Endothelial Dystrophy

A

accelerated endothelial cell loss

lack of cells results in edema

18
Q

Symptoms of Fuchs’ Endothelial Dystrophy

A

gradually progressive blur, usually worse in morning

19
Q

Signs of Fuchs’ Endothelial Dystrophy

A

guttata- beaten metal appearance of endothelial cells

20
Q

Course of Fuchs’ Endothelial Dystrophy

A

progresses from stromal edema to epithelial edema to epthelial edema that can rupture

21
Q

Mx of Fuchs’ Endothelial Dystrophy

A

Na Cl 5%, decrease IOP, hairdyer to dehydrate cornea
BCL, antibiotics, lubricants if epithelium ruptured
post lamellar or penetrating keratoplasty for scarring

22
Q

Posterior Polymorphous Corneal Dystrophy

A

focal abnormal developmental differentiation of endothelial cells
subtle epithelial lesions
associated with glaucoma and peripheral anterior synechia

Anterior Segment Disease (19 decks)

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