Corneal Degenerations Flashcards

1
Q

Corneal Degeneration

A

age related changes that affect the peripheral > central portion of the cornea
often unilateral with vascularization
no treatment required

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2
Q

Corneal Arcus

A

lipid deposits in circumferential stromal band near limbus

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3
Q

Concerns of Corneal Arcus

A

check for hyperlipidemia if appearing under age 40
dyslipidemia for younger patients
check for carotid disease on unaffected side if unilateral

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4
Q

Vogt Limbal Girdle

A

peripheral whitish crescents that may or may not touch limbus
bilateral but asymmetrical

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5
Q

Corneal Farinata

A

minute bilateral “flour dust” deposits in deep stroma

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6
Q

Crocodile Shagreen

A

gray-white polygonal stromal opacities separated by clear spaces
norm in ant 2/3 of stroma

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7
Q

Band Keratopathy

A

deposits of calcium in and adjacent to Bowman’s layer

begins nasal and temporal and extends centrally

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8
Q

Salzmann’s Nodular Degeneration

A

formation of opaque hyaline nodules anterior to Bowman’s

idiopathic or with chronic irritation/ inflammation

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9
Q

Tx for Salzmann’s Nodular Degeneration

A

address underlying cause
lubrication
keratectomy

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10
Q

Cystinosis

A

AR disorder resulting in accumulation of cystine crystals in many organs of body
all forms show cystine crystal deposits in cornea

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11
Q

Infantile Cystinosis

A

presents in 1st year with renal failure by age 10

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12
Q

Late Onset Juvenile Cystinosis

A

occurs later in childhood with renal failure as late teen or early adult

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13
Q

Adult Cystinosis

A

often benign and incidentally discovered with SLE

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14
Q

Tx of Cystinosis

A

cysteamine

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15
Q

Wilson Disease

A

AR disorder causing copper accumulation in liver, brain, cornea
causes liver dysfunction and Parkinson’s

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16
Q

Kayser Fleischer Ring

A

golden brown ring around limbus
copper in descemet’s membrane
indicative of Wilson’s when present with sunflower cataract

17
Q

Tx for Wilson Disease

A

penicillamine, zinc, ammonium tetrathiomolybdate

18
Q

Fabry Disease

A

XLR disorder causing enzyme deficiency resulting in glycolipid accumulating in tissues

19
Q

Ocular Signs of Fabry Disease

A

vortex keratopathy