2. NK Cells and YQ T Celss Flashcards
1
Q
How do NK Cells recognize their targets?
A
by the lack of MHC I
2
Q
NK Cells are sensitive to…
A
Fc Receptors
3
Q
What are the Activating receptors on NK Cells
A
NKG2D
CD16 (low affinity IgG Fc)
4
Q
What are the Inhibiting receptors on NK Cells
A
NKG2A
KIR Family
5
Q
What does KIR bind to?
A
MHC I
Detects healthy self tisue
6
Q
What are 3 things that activate NK Cells?
A
Target cell
Leukocyte
Cytokines
7
Q
Name 3 things of Innate activating NK Cells
A
2 signals
MHC surveillance
stress ligands
8
Q
Name 2 things of Adaptive mechs Activate NK Cells.
A
Single Signal
Ig targeting
9
Q
What is the role of yd T Cells?
A
remove diseased and malignant cells
10
Q
What do CD1 express?
A
Self and
non-self lipids
