Gastric-Oesophageal Cancer Flashcards
what are the features of gastric cancer
haemetemesis, melena, abdo pain, early satiety, vomiting
what does a high urea on its own suggest
upper GI bleed
what is boerhaaves
spontaneous rupture of the lower oesophagus
what is the treatment for oesophageal cancer
laparoscopic oesophagectomy
what is p53
a tumour supressor
what happens to the telomeres when cells divide
shorten, loose protection of chromosomes which can lead to mutation and duplication problems
what cells line the oesophagus
stratified squamous epithelium
what cells line the stomach
columnar epithelium
what is the Z line
junction between oesophagus and stomach, junction between stratified squamous and columnar epithelium
why do you get columnar epithlium cancer in oesophagus in the west
barretts oesophagus, obesity
what causes SCC in the oesophagus
primary injury: smoking, food, alcohol
what type of cancer is adenocarcinoma
columnar epithelium cancer
what is the therapy for a non resectable cancer
stent and radiotherapy
what type of cancers are sensitive to radiotherapy
squamous cell cancers
how is PET-CT used in cancer staging
sensitive to metastases
