Final - Chapter 22 Flashcards

1
Q

H. influenzae meningitis mostly occurs in

A

children

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2
Q

prevention on H influenzae meningitis

A

Hib vaccine

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3
Q

What is responsible for H. infuenzae meningitis?

A

capsule antigen type B

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4
Q

Type of meningitis common in children and young adults

A

meningococcal meningitis (neisseria meningititis)

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5
Q

Extra symptom of meningococcal meningitis

A

petichiae (rash)

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6
Q

Diagnosis of meningitis:

A
  1. spinal tap
  2. CSF sample
  3. Gram Stain
  4. Cultures/serology
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7
Q

treatment of meningitis

A

3rd gen cephalosporin

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8
Q

What grows in deep wounds

A

tetanus

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9
Q

What does tetanospasmin do

A

blocks the relaxation pathway and the NMJ

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10
Q

Tetanospasmin is an

A

A-B toxin

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11
Q

Symptoms of tetanus

A
  • general restlessness
  • irritability
  • stiff neck
  • lock jaw
  • opsithonis
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12
Q

Mechanism of botulinum toxin

A

An A-B toxin that blocks the release of Ach at the NMJ

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13
Q

symptoms of botulinum

A
  • flaccid paralysis
  • nausea
  • blurred vision
  • diarrhea
  • respiratory and cardiac failure
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14
Q

Botulinum toxin can come from

A

canned foods

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15
Q

How is polio spread

A

fecal oral route

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16
Q

Does transient viremia show symptoms of polio

A

no

17
Q

Persistant viremia causes

A

paralysis from the death of motor cells. Can also cause death from respiratory failure

18
Q

Salk vaccine

A
  • Inactivated vaccine
  • requires series of injections
  • consists of 3 killed viruses
19
Q

Sabin vaccine

A
  • weakened strains
  • liquid drops (Oral)
  • Less expensive
20
Q

Drawback of Sabin vaccine

A

1/750 000 actually caused the disease