Cell Cycle And Cancer Flashcards
List the cell cycle in order
G1, S, G2, mitosis, cytokenises
List the stages of mitosis in order
Prophase, metaphase, anaphase, telophase/cytokinesis
What happens during the G1 phase?
Growth of cell
What happens during S phase?
Replication of DNA
What happens during G2 phase?
Growth and preparation for mitosis.
What happens during prophase?
- Chromosomes become visible and are joined at the centromere
- Nuclear membrane and nucleolus disappear
- Spindle fibres form and attach to the centromere
- Centrioles move to the poles
What happens during metaphase?
Chromosomes are moved into a line across the middle of the cell by the spindle fibres.
What happens during anaphase?
Spindle fibres shorten, separating the sister chromatids at the centromere. Daughter chromosomes move towards the opposite poles of the cell.
What happens during telophase?
- Chromosomes are now at the opposite poles and start de condensing
- Division of the cytoplasm starts
- Nuclear membrane and nucleolus reform
What is the result of cytokinesis?
Two identical daughter cells.
What is cytokinesis for plant cells?
After the chromosomes have moved to the poles of the cell, a cell plate begins to form
-the cell plate turns into a new cell wall, leading to the creation of two new daughter cells
What happens to an animal cell during cytokinesis?
- After the chromosomes have moved to the poles of the cell, the cell membrane pinches inward, forming a cleavage furrow
- the furrow continues to pinch inward, dividing the cell in two
What is cancer?
Cancer cells are cells that divide uncontrollably.
Why do cancer cells form?
Cancer cells form when a cell’s DNA is changed or damaged and therefore mutated. Mutations can be caused by environmental factors, or can be inherited.
Identify some differences between normal and cancer cells.
- normal cells reproduce for about 50-60 cell divisions, cancer cells never stop reproducing
- normal cells stick together to form masses of cells when appropriate, cancer cells do not stick to other cells and behave independently
- normal cells self-destruct when too old or damaged, cancer cells may move to another part of the body.