Serum Tumor Markers p.220 p.44 and Hypothalamic/Thalamic Nuclei p. 466-468 Flashcards

1
Q

CA 15-3

CA 27-29

A

Breast Cancer

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2
Q

CA 19-9

A

Pancreatic Adenocarcinoma

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3
Q

CA 125

A

Ovarian Cancer

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4
Q

Calcitonin

A

MEDULLARY Thyroid Cancer - alone and in MEN2A/2B

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5
Q

CEA

A

CarcinoEmbryonic Antigen - Very nonspecific

Major associations: Colorectal and Pancreatic Cancers

Minor associations: Gastric, Breast, and Medullary Thyroid Carcinoma

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6
Q

Chromogranin

A

Neuroendocrine Tumors

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7
Q

PSA

A

Prostate cancer

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8
Q

P-Glycoprotein

A

Multidrug Resistant Protein (MDR1)
Adrenocortical Carcinoma

Also expressed in other cancers (Colon, Liver)
Pumps out chemotherapy to make it drug resistant

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9
Q

Vimentin

A

Mesenchymal Tumors - SARCOMA

Endometrial Carcinoma
Renal Cell Carcinoma
Meningioma

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10
Q

Desmin

A

Muscle Tumors

Rhabdomyosarcoma

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11
Q

Cytokeratin

A

Epithelial Tumors

Squamous Cell Carcinoma

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12
Q

GFAP

A

Neuroglial Tumors - Astrocytes, Schwann Cells, Oligodendrocytes

Astrocytoma, Glioblastoma

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13
Q

Neurofilaments

A

Neuronal Tumors

Neuroblastoma

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14
Q

Lateral Area of Hypothalamus

A

Hunger
Destruction –> Anorexia

Stimulated by Ghrelin
Inhibited by Leptin

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15
Q

VMA of Hypothalamus

A
Satiety
Destruction (i.e. Craniopharyngioma) --> Hyperphagia

Stimulated by Leptin

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16
Q

Anterior Hypothalamus

A

Cooling - Parasympathetic

A/C = Cooling

17
Q

Posterior Hypothalamus

A

Heating - Sympathetic

18
Q

Suprachiasmatic Nucleus

A

Circadian Rhythm

19
Q

Supraoptic and Paraventriular Nuclei

A

Synthesize ADH and Oxytocin

20
Q
Ventral PosteroLateral (VPL) 
(Thalamus)
A

Spinothalamic and Dorsal Columns
Medial lemniscus

VPL: Vibration, Pain, Pressure, Proprioception
Light touch, Temperature

21
Q
Ventral PosteroMedial (VPM)
(Thalamus)
A

Trigeminal and Gustatory Pathway

Face sensation, Taste

22
Q

Lateral Geniculate Nucleus

Thalamus

A

CN II
Vision

Sends info to Calcarine Sulcus
Lateral = Light

23
Q

Medial Geniculate Nucleus

Thalamus

A

Hearing

Sends info to Auditory cortex of Temporal Lobe
Medial = Music

24
Q

Ventral Lateral Nucleus

Thalamus

A

Basal Ganglia, Cerebellum
Motor

Sends info to Motor Cortex