Mental Health Drugs_Contra-indications/Side effects/withdrawal

Question 1

Benzodiazepines abrupt withdrawal safe?

Answer 1

If physical dependence exists then abrupt withdrawal may result in benzodiazepine withdrawal

Question 2

Lithium Contra-Indications?

Answer 2

Addison's disease
Cardiac insufficiency
Dehydration
Family/personal history of brugada's syndrome
Low sodium diet
Rhythm disorder
Untreated hypothyroidism

Question 3

Abrupt withdrawal of Lithium?

Answer 3

Not recommended
If lithium is to be discontinued, the dose should be reduced gradually over a period of at least 4 weeks (preferably over a period of up to 3 months).

If stopped abruptly consider switch to antipsychotic or valproate

Question 4

Benzodiazepines Contra-Indications?

Answer 4

Acute pulmonary insufficieny
Marked Neuromuscular weakness
Sleep apnoea Syndrome
Unstable myasthenia Gravis
Not for use alone to treat chronic psychoses
Not for use alone to treat chronic depression (or associated anxiety)
Respiratory Depression

Question 5

Abrupt withdrawal of Fluoxetine?

Answer 5

Not recommended

Question 6

Clozapine Abrupt withdrawal?

Answer 6

Not recommended

On planned withdrawal reduce dose over 1-2 weeks to avoid risk of rebound psychosis

Question 7

SSRI Common Side effects BNF

Answer 7

Abdo pain
constipation
diarrhoea
GI effects
Nausea
Vomiting

Question 8

Benzodiazepines Side effects?

Answer 8

Amnesia
Ataxia
Confusion
Dependence
Drowsiness next day
lightheadedness next day
Muscle weakness
Paradoxical increase in aggression

Question 9

Fluoxetine Contra-Indication

Answer 9

Poor controlled epilepsy

Patients in manic phase

Question 10

Clozapine Contra-indications

Answer 10

Alcohol and Drug Psychosis
Bone Marrow disorders
Coma
History of Agranulocytosis
History of circulatory collapse
History of neutropenia
Paralytic Ileus
Severe Cardiac Disorders
Severe CNS depression
Uncontrolled Epilepsy

Question 11

Clozapine Side effects?

Answer 11

Anorexia; 
constipation; 
hypersalivation; 
malaise; 
speech disorders; 
urinary incontinence

Question 12

Fluoxetine Very Common Side effects - medicines.org

Answer 12

Sleep problems
Headache
nausea
diarrhoea
tiredness

Question 13

Fluoxetine Common side effects - medicines.org

Answer 13

anorexia
weight loss
akathisia
decreased libido/erectile dysfunction
Sleep disturbances
diaphoresis
tremor
rapid/irregular heartbeat
flushing