69

Question 1

Normal Flora of Skin (3)

Answer 1

E. coli (-)
Mycococcus luteus (+)
Staphylococcus epidermis (+)

Question 2

Skin Diseases in Epidermis

Answer 2

Folliciiulitis
Impetigo
Acne
SSSS-TSS

Question 3

Skin Diseases in Dermis

Answer 3

Carbuncles
Furuncles
Ecthyma

Question 4

Skin Diseases in Sub Q Tissue

Answer 4

Carbuncles
Furuncles
Cellulitis
Erysipelas
Necrotizing Fasciitis

Question 5

Skin Diseases in Muscle

Answer 5

Myonecrosis

Question 6

Causative agent of acne vulgaris (gram, shape, O2 req.)

Answer 6

Propionibacterium acnes
(+)
pleomorphic
NF
Areotolerant

Question 7

Causative agent of folliculitis & type each causes

Answer 7

S. aureus (folliculitis barbae, Sty)

P. aeruginosa (systemic - hot tub)

Question 8

Proteins/Virulence Factors of S. aureus (5)

Answer 8

Hemolysin
Coagulase
Leukocidin
Protein A
MSCRAMMs (fibronectin binding protein & clumping fact)

Question 9

Toxins Produced by S. aureus

Answer 9

Exfoliatin A & B
-causes outer layer of skin to slough off
Pyrogenic (TSST-1)

Question 10

S. aureus Characters

Answer 10

(+)
NF (axilla, nares, groin)
catalase (+)
B-hemolytic

Question 11

P. aeruginosa Characters

Answer 11

(-)
opportunistic
Pyocyanin & pyoverdin

Question 12

Another term or furuncle

Answer 12

Boil

Question 13

Causative Agent of Furuncle

Answer 13

S. aureus

Question 14

Where to furuncles develop?

Answer 14

Where hair follicles are exposed to friction and perspiration

Question 15

Skin level(s) of furuncle?

Answer 15

Dermis & Sub Q (abscess)

Question 16

What is a carbuncle?

Answer 16

Aggregate of connected furuncles

Question 17

Causitive agent of carbuncle?

Answer 17

S. aureus

Question 18

Treatment of furuncles & carbuncles

Answer 18

warm compress, drain, AB

Question 19

Varients of pyoderma?

Answer 19

Impetigo (bullous and non-bullous)

Ecthyma

Question 20

What is pyoderma?

Answer 20

Bacterial skin inflammation marked by pus filled lesions

-dermis & epidermis

Question 21

Causative agents of non-bullous impetigo

Answer 21

S. aureus (most common)

GAS (ex. S. pyogenes)

Question 22

Virulance Factors of GABHS (S. pyogenes)

Answer 22

Streptococcal Pyrogenic Exotoxins
-superantigens that cause rash
M protein
-creates sequelae (rheumatic fever, glomerulonephritis)
DNAase
Hyaluronidase
Streptokinase (dissolbes blood clots)

Question 23

Clinical Manifestations of Nonbullous Impetigo

Answer 23

Intraepidermal lesions

Erythematous macule to vesicle to rupture to yellow crust exudate

Question 24

Spread of nonbullous impetigo

Answer 24

Very infectious, spreads rapidly, bacteria in vesicle, trx to decrease spread

Question 25

Causative agent of bullous impetigo

Answer 25

S. aureus

Question 26

Clinical Manifestations of bullous Impetigo

Answer 26

Begins as vesicle, enlarge to form bullae clear/yellow fluid, become turbid, rupture and brown crust forms

Question 27

Population and area of body with nonbullous impetigo

Answer 27

2-6yo | Face, arm, legs

Question 28

Population and area of body with bullous impetigo

Answer 28

2-6yo | face, legs

Question 29

Caustive Agent of Ecthyma

Answer 29

GAS

Question 30

Clinical Manifestations of Ecthyma

Answer 30

Ulceraters c green/yellow crust, raised margins | Dermis

Question 31

Is ecthyma contagious?

Answer 31

Rarely

Question 32

Population and area of body with Ecthyma

Answer 32

``` Children, DM, neglected elderly Lower extremities (most common) ```

Question 33

TRX of impetigo & ecthyma

Answer 33

Inc. hygiene Debride Topical & oral AB

Question 34

Population with cellulits

Answer 34

middle age & older adults

Question 35

Population with erysipelas

Answer 35

young children & older adults

Question 36

Most common causitive agent of Cellulits

Answer 36

GABHS

Question 37

Causative agents of Cellulits

Answer 37

GABHS + (associated c skin lesions - ex: varicella) S. aureus + (does NOT spread as fast as others & assoc. c local abscess) Acinetobacter baumanii - (associated c trauma & invasive devices) Pasteurella multocida - (associated c dog/cat bite & purulent drainage) Aeromonas hydrophila - (associated c freshwater contamination of wound) Vibrio vulnificans - (associated c saltwater contamination of wound)

Question 38

Hallmark S&S of Cellulits

Answer 38

HEET | Heat, erythema, edema, tenderness

Question 39

Layer of Skin Involved in Cellulits

Answer 39

DEEP dermis & Sub Q

Question 40

What should you avoid in cellulitis trx?

Answer 40

NSAIDs (mask indicators of worsening disease)

Question 41

Trx of Cellulits

Answer 41

Elevate, immobilize, keep skin moist, AB (oral)

Question 42

What is erysipelas?

Answer 42

Special form of cellulitis that is caused mainly by GAS and rarely by S. aureus. Found in UPPER dermis & superficial lymphatics(as compared to DEEP of cellulitis)

Question 43

S&S of Erysipelas

Answer 43

Raised lesions with clear lines of demarcation. Milian's ear sign (distingguishing feature) Const. symptoms

Question 44

Anatomical regions of erysipelas

Answer 44

Lower extremities & butterfly rash common

Question 45

Trx of erysipelas

Answer 45

elevate, immobilize, keep skin moist, AB (parenteral)