General topics Flashcards

1
Q

recommended margins for excisional biopsy for small BCC or SCC ?

A

4-5 mm

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2
Q

Acantosis nigricans is ?

A

A paraneoplastic disease.

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3
Q

The primary skin chromphores are ?

A
  • Water.
  • Hemoglobin.
  • Melanin.
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4
Q

Cryosurgery?

A

is the process of destroying a skin lesion by freezing it with liquid nitrogen.

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5
Q

Biopsy site for ulcerated/necrotic lesion?

A

Edge of ulcer or necrosis plus adjacent skin.

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6
Q

Raynaud’s phenomenon can be found in ?

A
  • Systemic sclerosis.
  • SLE.
  • Dermatomyositis.
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7
Q

What should be controlled during methotrexate therapy ?

A

Liver enzymes, morphology, lipids.

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8
Q

Herald pach is typical for ?

A

Pityriasis rosea

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9
Q

recommended margins for excisional biopsy for melanoma?

A

5mm

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10
Q

Necrobiosis lipoidica is?

A

a disease is strongly associated with diabetes mellitus.

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11
Q

Compulsive plucking of the hair is known as?

A

Trichtillomamania.

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12
Q

What is the most important role in the protection against transepidermal water loss is played by ?

A

Cornified layer

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13
Q

recommended margins for excisional biopsy for benign lesion?

A

1-2 mm

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14
Q

The target chromphore in vascular lesions is ?

A

Oxyhemoglobin.

- absorption peaks at 418,542 and 577 nm.

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15
Q

recommended margins for excisional biopsy for atypical nevi?

A

3-4 mm

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16
Q

Kobner phenomenon in ?

A
  • Psoriasis.
  • LP.
  • Common warts.
  • Plane warts.
  • Could also be seen in Erythema multiforme.
17
Q

Pityriasis versicolor is caused by:

A

Malassezia furfur, the pathogenic form of pityrosporum oval.

18
Q

The most common indication for Q-switched laser?

A

Removing tatoos.

19
Q

Lammellar ichtyosis ?

A
  • Defect of transglutaminase 1.
  • oral retinoids, glycolic acid.
  • May lead to blindness.
  • Halequin ichtyosis: usually fatal, oral retinoids.
20
Q

Nikolsky’s sign is positive in ? ( name all )

A
  1. SSSS.
  2. TEN ( or Lyell syndrome ).
  3. SJS.
  4. Pemphigus vulgaris.
  5. Generalized psoriasis pustulosa (Von zumbusch).
  6. Burns.
21
Q

Scarring (cicatricial) alopecia can be present in :

A
  • Frontal fibrosing alopecia.
  • Lichen planopilaris.
  • Cutaneous lupus erythematous.
22
Q

What is the most common used technique for obtaining a skin specimen for histologic examination ?

A

Shave biopsy.

23
Q

Biopsy site for small vessels vasculitis ?

A

Characteristic lesion of recent onset.

24
Q

Biopsy site for blister ?

A

Edge of lesion, including perilesional skin.

25
Q

burrow is the primary lesion of ?

A

Scabies

26
Q

Target-like lesion is characteristic for :

A

Erythema multiforme.

27
Q

What disease can be misdiagnosed as vitiligo ?

A

Pityriasis versicolor

28
Q

Pathergy can occur in ?

A
  • Pyoderma gangrenosum.
29
Q

Biopsy site for tumor ?

A

Thickest portion, avoid necrotic tissue.

30
Q

Biopsy site for generalised polymorphous eruption?

A

Characteristic lesion of recent onset.

31
Q

Hertog sign?

A

less hair laterally on eyebrow.

32
Q

recommended margins for excisional biopsy for invasive melanoma?

A

depends on breslow depth, e.g. 1cm for <1mm

33
Q

Under wood’s light, what color can we observe with:

  • Microssporum?
  • Trichophyton violaceum?
  • Malassezia furfur?
A
  • Microssporum: Green
  • Trichophyton violaceum: Doesn’t fluoresce.
  • Malassezia furfur: Yellow