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Pharma Oral > 57. Anti-helmintics part 2 > Flashcards

57. Anti-helmintics part 2 Flashcards

1
Q

Salicylanilidies

A

Brotianide
LCosantel
Niclosamide
Rafoxanide

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2
Q

Substituted phenols

A 
Bithinol
Disophenol
Dichlorophene
Nitronixil
Hexachlorophene
Niclofolan
Diamphenetide (immature fluke)
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3
Q

Salicylanilidies + substituted phenols

A

Anti-trematodes, anti-cestodial, (anti-nematodial)
Moa: uncoupling of the ox-phos process
Spectrum: sheep+ cattle
PK: liver + bile secretion (fluke)
> bile secretion contains active metabolites: reached by mature fluke
App: PO except nitronixil: Sc

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4
Q

Isoquinolin + benzazepin derivatives

A 
AC and some AT
Praziquantal
epsiprantal
Moa: spastic paralysis
Spect: mature + larval anti-cestodial, some trematodes
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5
Q

Clorsulon

Liver fluke

A

Liver fluke
Inhibits enzymes of glycolytic pathway
Not dairy cows
sheep + cattle (+ivermectin)

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6
Q

Bunamidine salts

A 
Anti-cestodal
Use: small animals
Inhibits glucose uptake in tapeworms
Give after fasting
Se: vomiting and diarrhoea
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Pharma Oral (12 decks)

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