7. protein synthesis Flashcards
(14 cards)
isoaccepting tRNA
tRNAs with different anticodons that carry the same amino acid
aaRS
aminoacyl tRNA synthetase
catalyses covalent bond formation between an amino acid and tRNA
energy source in cells
ATP and GTP
kozak sequence
conserved sequence around AUG initiation codon in eukaryotes
Shine-Delgano sequences
sequence in 5’ UTR of prokaryotic mRNAs that bind to 16S rRNA
Polycistronis mRNA
mRNA that contains multiple open reading frames
molecular mimicry
when two different molecules can perform similar functions because they have the same shape
GGQ
sequence motif in eRF1 that catalyses release of polypeptide from ribosome
Polysome
a group of ribosomes bound to a single mRNA molecule
Integrated stress response
a mechanism for cells to inhibit translation in response to cellular stress
chloramphenicol
antibiotic that inhibits translation (prokaryotes)
puromycin
inhibitor of translation (prokaryotes and eukaryotes)
ricin
inhibitor of translation (eukaryotes)
rifampicin
antibiotic that inhibits transcription (prokaryotic)