K7 HGMS Flashcards

1
Q

Beschreiben Sie das Prinzip des HGMS (High Gradient magnetic separation)

A
  • Zugabe von Magnetadsorbern in das Medium
  • Bindung des Proteins an die Absorber durch einen spezifischen Ligand
  • Trennung der beladenen Absorber durch Magnetfeld
  • Washing and Elution

Beispiele Anwendung

  • Zellsortierung
  • DNA Separation
  • Bioanalyse
  • Drug Targeting
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2
Q

Partikel HGMS

A
  • Größe ca 100 mikrometer
  • Herstellungsprozess
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3
Q

Aufbau eines Partikels

A
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4
Q

Liganden Magnetischer Adsorber

A
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5
Q

Kinetik HGMS

A
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6
Q

Hintergrund magnetisches Fled

A
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7
Q

Aufbau Magnetseparator

A
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8
Q

Prozessentwicklung

A
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