Neuro-Antibiotic Drugs Flashcards
What is the empiric treatment for a community acquired subdural empyema
Ceftriaxone/cefotaxime + vancomycin + metronidazole
What is the empiric treatment for a nosocomial acquired subdural empyema
Meropenem + vancomycin
When is vancomycin used in the treatment for brain abscesses
Until it has been shown to not be MRSA
Wht does penicillin G cover with regards to brain abscess
Aerobic and anaerobic streptococci (mouth flora)
What is the empiric treatment for acute pyogenic meningitis in patients that are immunocompromised
Vancomycin + ampicillin + cefepime/meropenem
Which drugs can be used for a brain abscess complication during a neurosurgery or P. Aeuriginosa
Ceftazidime, cefepine, meropenem
What is the empiric treatment for acute pyogenic meningitis in patients with Beta lactam allergy >50
Vancomycin + moxifloxacin + TMP/SMX
What is the empiric therapy of a patient with a brain abcess from an unknown source
Vancomycin + Ceftriaxone/cefotaxime + metronidazole
What do the third generation cephalosporins cover with regards to brain abscess treatment
- most aerobic and microaerophilic strep
- enterobacteriaceae
What is the treatment of fungal meningoencephalitis during the consolidation period of therapy
Fluconazole
What is the empiric treatment for acute pyogenic meningitis in neonates
Aka E. Coli and Strep B
-Cefotaxime/Ceftriaxone + Vancomycin
What does metronidazole cover with regards to brain abscess treatment
Most because it is able to penetrate the brain abscesses
What is the treatment of fungal meningoencephalitis during the induction period of therapy
Amphotericin B + flucytosine
Which drug is replaced and what is the replacement in the cause of a brain abscess that does not contain MRSA
Vancomycin is replaced with nafcillin or oxacillin
What is the empiric treatment for acute pyogenic meningitis in adolescents and young adults
Aka Neisseria menigitidis
-Cetotaxime/Ceftriaxone + vancomycin
