Skeletal Muscle And Nerve Tissue Histo Flashcards

1
Q

Skeletal muscle

A
Striated 
Multinucleated
Fatigable 
Voluntary
Quick
Strong
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2
Q

Myofiber

A

A group of myofibrils surrounded by endomysium
Muscle Cell
Myocyte

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3
Q

Myofibrils

A

Groups of sarcomeres

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4
Q

Sarcomeres

A

Contractile group made of actin and myosin myofilaments

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5
Q

Actin

A

Thin filaments
Made of f-actin monomers
Monomers come together to form actin filaments (in double stranded rings)
Uses nebulin to determine length of filament
Tropomyosin is intertwined in actin filament
Troponin is bound to tropomyosin blocking the myosin binding site

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6
Q

Myosin

A

Thick filaments
Has 2 heavy chains and 2 light chains
Heavy chains contain ATPase domain, actin binding sites, and myosin heads
Connected to Z disk via titin

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7
Q

Fascicle

A

Group of myofibers

Surrounded by perimysium

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8
Q

Muscle

A

Group of fascicles

Surrounded by epimysium

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9
Q

Sequence of what makes a muscle

A
Myosin and actin myofilaments
Sarcomere
Myofibril
Myofiber
Fascicle
Muscle cell
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10
Q

Z disk

A

Sarcomere is Z disk to Z disk

Contains actin and myosin

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11
Q

M line

A

Where myosin attaches

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12
Q

H zone

A

Contains no thin filaments

Changes size during contraction

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13
Q

I band

A

Contains no myosin

Changes size during contraction

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14
Q

A band

A

From the end of one myosin head to the end of an adjacent myosin head
Does not change size during contraction

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15
Q

Muscle Contracttion

A

Ca2+ is released by the sarcolemma and binds to troponin
Causes conformational change
Troponin lets go of tropomyosin
Myosin binds to actin and crawls across actin
Myosin and actin do NOT change size
H zone and I band shorten
Z disk to Z disk becomes closer
all myofibrils in a muscle contract at the same time making the entire muscle shorten

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16
Q

Skeletal muscle fiber types

A

Type I
Type IIa
Type IIb

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17
Q

Type I muscle fiber

A
Slow, not very powerful
Many mitochondria
Great deal of myoglobin
Aerobic respiration
Slow fatiguability
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18
Q

Type IIA muscle fiber

A
Intermediate speed and power
Many mitochondria
Many myoglobin
Intermediate fatiguability
Aerobic respiration (less O2 necessary than type I)
19
Q

Type IIb muscle fiber

A
Quick, very powerful
Few mitochondria
Few myoglobin
Quick fatiguability 
Anaerobic respiration
20
Q

Sarcolemma

A

Membrane surrounding muscle cell

21
Q

Transverse (T) tubule

A

Perforated muscle cells so electrical transmission can go from sarcolemma to muscle cell

22
Q

Sarcoplasmic Reticulum (SR)

A

Acts as a smooth ER for muscle cells
Has terminal cisternae
Holds Ca2+

23
Q

Terminal cisternae

A

Flattened sac of SR on either side of a T tubule

24
Q

Triad

A

T tubule and 2 terminal cisternae (one on each side)

25
Q

End feet

A

Connect T tubules with SR to allow Ca2+ release

26
Q

Neuromuscular junction

A

Skeletal muscle innervated by alpha motor neurons from anterior horn of spinal cord
1 nerve per muscle cell
1 nerve can supply many muscle cells

27
Q

Extrafusal fibers

A

Part of neuromuscular spindle apparatus

Contract muscles

28
Q

Neuromuscular spindle appparatus

A

Reflexive response preventing overstretching of muscle

29
Q

Intrafusal fibers

A

Sense length change in muscle fibers

Inside extrafusal fibers

30
Q

Type Ia sensory muscle fibers

A

Afferent innervation in intrafusal fibers

Send signals to extrafusal and intrafusal muscle fibers

31
Q

Alpha motor neurons

A

Efferent fibers from anterior horn of spinal cord causing contraction of extrafusal muscle fibers

32
Q

Gamma motor neurons

A

Efferent neurons from anterior horn causing contraction of intrafusal muscle fibers

33
Q

Soma/body of neuron

A

Contains all neuron organelles

34
Q

Nissle substance

A

Abundant ribosomal ER in cytoplasm of soma/body of neurons

35
Q

Dendrites

A

Receive signals from other neurons

36
Q

Axon hillock

A

Connect soma/body with axon

Accumulates all electrical signals from dendrites to send them down the axon

37
Q

Axon

A

Sends electrical signals from neuron to synapse

38
Q

Synapse

A

Transfers electrical impulse from the neuron to the target tissue

39
Q

Neuron types

A

Multipolar
Bipolar
Psueodunipolar

40
Q

Multipolar

A

Multiple dendrites and one axon

41
Q

Bipolar

A

1 dendrite (multiple extensions) and 1 axon

42
Q

Pseudounipolar

A

1 dendrite and 1 axon, but cell body is separated from both

43
Q

Myelination

A

Schwann cells-PNS
Oligodendrocytes-CNS
Transmits electrical signal faster