Histology - Epithelia Flashcards

1
Q

What are the 4 basic tissue types

A

Epithelia; connective; muscle; nervous

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2
Q

What is the purpose of surface epithelia

A

Covers or lines surfaces, cavities and tubes

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3
Q

What are epithelia cells composed of

A

Closely aggregated, polyhedral epithelial cells with a minimum of intercellular substance

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4
Q

What is the adhesion between cells like

A

It is strong; thus cellular sheets are formed

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5
Q

What layer of the skin is made up of epithelial cells

A

The epidermis

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6
Q

What are 3 common features of epithelial cells

A

Usually polarised; bind together in sheets; non-vascular

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7
Q

Name 3 functions of epithelia

A

Mechanical barrier (skin); absorption (lining of intestine); locomotion (cilia in oviduct)

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8
Q

Name the 2 types of cellular components that are vital to the function of epithelia

A

The cytoskeleton; intercellular junctions

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9
Q

Name the 3 classes of filaments that form the cytoskeleton in cells (smallest to biggest)

A

Microfilaments (5 nm); intermediate filaments (~10 nm); microtubules (25 nm)

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10
Q

What are microfilaments composed of

A

Fine strands of the protein actin

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11
Q

What are microfilaments’ main functions

A

Anchorage, movement and extension of the cell membrane

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12
Q

What are intermediate filaments’ main functions

A

Bind intercellular elements together and to the cell membrane

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13
Q

What are microtubules composed of

A

2 types of tubulin subunits; alpha and beta

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14
Q

What are microtubules important for

A

Movement of components in the cell and during cell division

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15
Q

What are intercellular junctions

A

Specialised membrane structures that link individual cells together into a functional unit

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16
Q

Name the 3 types of junctions found in epithelial cells

A

Occluding; anchoring; communicating

17
Q

What are occluding junctions’ main functions

A

Inhibit diffusion; the focal region of close apposition between adjacent cell membranes

18
Q

Name the 2 forms of anchoring junctions

A

Zonunla adherens; desmosomes

19
Q

Describe how zonula adherens hold cells together

A

Link tightly onto opposite cells

20
Q

How do desmosomes hold cells together

A

Link submembrane intermediate filaments of adjacent cells together

21
Q

What do communicating junctions (gap junctions) allow between cells

A

Selective diffusion of small molecules and ions

22
Q

Describe the structure of each junction

A

Circular patch studded with several hundred pores

23
Q

What is an area with close association of several junction types called

A

A junctional complex

24
Q

What are the 3 epithelial cell shapes

A

Squamous; cuboidal; columnar

25
Q

What is one layer of epithelial cells called

A

Simple layer

26
Q

What are several layers of epithelial cells called

A

Stratified

27
Q

Describe what pseudostratified is

A

Appears stratified but all cells contact basal lamina

28
Q

What are microvilli’s main function and roughly how big are they

A

Increase the surface area of the cell membrane; 0.5-1 micro metres

29
Q

What are cilia’s main function and roughly how big are they

A

Propel mucous or fluid over the cell surface; up to 10 micro metres

30
Q

What are keratins

A

Group of tough structural proteins; dead material that accumulates