Autoantibodies + Rheum Flashcards

1
Q

Addisons Autoantibodies

A

Anti-21-hydroxylase

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2
Q

Anti-phospholipid syndrome Autoantibodies

A

Anti-cardiolipin

Lupus anticoagulant

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3
Q

Autoimmune haemolytic anaemia Autoantibodies

A

RBC Autoantibodies (Classified as warm or cold depending on what temperature Autoantibodies attach to RBC)

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4
Q

Autoimmune hepatitis Autoantibodies

A

Anti-nuclear
Anti-smooth muscle
Anti-Liver/Kidney microsomal
pANCA

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5
Q

Churg strauss Autoantibodies

A

pANCA (MPO)

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6
Q

Coeliac Autoantibodies

A

Anti-endomysial
Anti-tissue transglutaminase
Anti-gliadin

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7
Q

Scleroderma Autoantibodies

A

Rheumatoid factor
ANA
Anti-centromere

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8
Q

Goodpasture’s Autoantibodies

A

Anti-glomerular basement membrane

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9
Q

Grave’s Autoantibodies

A

Anti-TSH receptor

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10
Q

Hashimoto’s thyroiditis Autoantibodies

A

TSH-receptor blocking antibodies

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11
Q

Myasthenia graves Autoantibodies

A

Anti-acetylcholine receptos antibodies

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12
Q

Pernicious anaemia Autoantibodies

A

Anti-parietal cell

Anti-intrinsic factor

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13
Q

Polyarteritis nodosa Autoantibodies

A

pANCA (MPO)

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14
Q

Poly/Dermatomyositis Autoantibodies

A

ANA
Rheumatoid factor
Anti-Jo

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15
Q

Rheumatoid disease Autoantibodies

A

Anti-CCP

Rheumatoid factor

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16
Q

Sjögren syndrome Autoantibodies

A

Rheumatoid factor
ANA
Anti-Ro
Anti-La

17
Q

SLE Autoantibodies

A

Anti-Doublestranded DNA
Rheumatoid factor
ANA
Anti-Ro

18
Q

Wegner syndrome (Granulomatosis with Polyangitis)

A

cANCA (PR3)

19
Q

Synovial fluid analysis of gout

A

(Remember ‘N’)

Negatively birefringent Needles of sodium urate

Cloudy appearance

20
Q

Synovial fluid analysis of pseudogout

A

(Remember P)

Positively birefringent rhomboids of sodium Pyrophosphate

cloudy appearance

21
Q

What is sicca and what assoc with

What test is diagnostic

A

Dry eyes seen in Primary Sjögrens or in assoc with other rheumatological conditions

Schirmer test: filter paper to lower eyelid and left for 5 mins (normally 10mm will become wet. Less = dry eyes)