Flashcard 10

1
Q

components of process of glycosylation

A
  1. accumulation of trapped plasma proteins

2. accumulation of cross-linked basal lamina proteins

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2
Q

potential causes of raised ACR

A
  1. UTI
  2. orthostatic proteinuria
  3. diabetic kidney disease
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3
Q

how does IGF-1 work

A

acts as an autocrine to stimulate cartilage production

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4
Q

medications that can cause a rapid rise in [BG]

A
  • steroids

- antipsychotic drugs

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5
Q

what defines a steroid hormone

A

all derived from cholesterol

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6
Q

4 areas producing steroid hormones

A
  • gonads
  • adrenal cortex
  • placenta
  • kidney
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7
Q

acidotic breathing

A

Kussmauls

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8
Q

DKA

A

diabetic ketoacidosis

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9
Q

how do osteoblasts work

A

highly active laying down extracellular matrix which they can calcify to form boooonnnneeee

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10
Q

thyrotoxicosis

A

excessive thyroid hormone of any cause

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11
Q

2 hypothalamic inhibiting hormones

A

dopamine

growth hormone inhibiting

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12
Q

what effect does somatostatin have on insulin and glucagon release

A

strongly suppresses

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13
Q

hyperthyroidism

A

excessive production of thyroid hormone by thyroid gland

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14
Q

how do G-protien coupled receptors work?

A

activates 2nd messenger system -> modification of existing protein

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15
Q

main function vasopressin

A

anti-diuretic hormone

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16
Q

where do non-trophic hypothalamic neurohormones go when they leave the hypothalamus

A

hypothalamic nerves -> posterior pituitary-> blood

17
Q

what 2 peptide neurohormones does the posterior pituitary store and release

A

vasopressin

oxytocin

18
Q

autocrine chemical

A

acts on/ in the same cell that synthesises the hormone

19
Q

main function oxytocin

A

milk ejection and uterine contraction

20
Q

how is an insulinoma indicated

A

elevated C peptide insulin level

21
Q

4 general categories for using lab tests?

A

diagnosis
monitoring
screening
prognosis