flashcard 7

1
Q

good differentiative sign between type 1+2 diabetes mellitus

A

type 2 will not be ketotic

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2
Q

hypothyroidism treatment

A

levothyroxine (tamper with dosage until levels are normal)

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3
Q

cretinism causes

A

iodine def

maternal hypothyroidism

genetic

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4
Q

goitre

A

enlarged thyroid gland

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5
Q

cushings disease

A

pituitary tumour causing excess corticosteroids

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6
Q

SYMPTOMS:

  • galactorrhoea
  • infertility
  • headache
  • hypogonadism
A

hyperprolactinaemia

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7
Q

cranial diabetes insipidus

A

hypothalamus does not produce enough ADH

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8
Q

severe cases outcomes of congenital adrenal hyperplasia

A
  • ambiguous genitalia

- neonatal salt-losing crisis

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9
Q

diagnose:

  • muscular weakness
  • polydipsia
  • polyuria
  • hypertension
  • K in urine increase
  • K in blood decrease
A

conns syndrome

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10
Q

long term symptoms:

  • hypertension
  • anxiety
  • sweating
  • headache
  • palpitations
  • tremor
A

phaechromocytoma

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11
Q

corticosteroid

A

any steroid hormone synthesised by adrenal cortex

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12
Q

investigations for all suspected thyroid cancers

A

biopsy

USS

FNAC

TFTs

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13
Q

mutation associated with follicular thyroid cancer

A

RAF

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14
Q

what does raised serum calcitonin suggest

A

medullary thyroid cancer

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15
Q

indications for surgery in hyperparathyroidism

A
  • hypercalcaemia symptoms
  • osteoporosis
  • recurrent kidney stones
  • eGFR <65
  • <50
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16
Q

what does MEN stand for

A

multiple endocrine neoplasia

17
Q

value determining hypercalcaemia

A

> 2.6

18
Q

mild hypocalcaemia management

A
  • treat underlying cause

- oral calcium tablets

19
Q

signs:

  • hypocalcaemia
  • high phosophate
  • high PTH
  • obese
  • short stature
  • short metacarpal bones
A

pseudo-hyperparathyroidism

20
Q

hypercalcaemia investigations

A

U+Es

  • ca
  • phosphate
  • PTH
  • ECG
  • albumin