Viruses Flashcards

1
Q

How are viruses classified?

A

according to their genome (single stranded/double stranded, RNA/DNA, sense/antisense)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the role of the virus protein capsid?

A

to protect the genome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where does the virus life cycle occur?

A

inside the host cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Define virus

A

obligate intracellular parasite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the seven viral groups?

A
  • dsDNA viruses
  • ssDNA viruses
  • dsRNA viruses
  • (+)sense RNA viruses
  • (-)sense RNA viruses
  • RNA reverse transcribing viruses HIV
  • DNA reverse transcribing viruses
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Name all the DNA virus families (HHAPPPy)

A
Hepadna
Herpes 
Adeno 
Pox 
Parvo 
Papova
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which DNA viruses have naked capsids?

Dina gets naked for her PAP smear

A
  • parvovirus
  • adenovirus
  • papovirus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are virons?

A

very small rod-like RNA molecules, only plant pathogens (CONTAIN NO PROTEIN)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are prions?

A

contain no NUCLEIC ACID

  • resistant to heat inactivation
  • resistant to radiation damage
  • resistant tp DNAase and RNAase Treatment
  • sensitive to urea, SDS, phenol and other protein denaturing chemicals
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the different types of capsid?

A
  • helical

- icosahedral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the four steps of virus replication?

A
  • entry
  • replication
  • assembly
  • release
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How do viruses attach to the cell?

A

via receptors called attachment proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What determines the outcome of infections?

A

the interaction of the outer surface of a virus with a cellular receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where do most DNA viruses replicate?

A

nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where do most RNA viruses replicate?

A

cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What determines how quickly the virus spreads?

A

the release (how many particles are released etc)

17
Q

What is the PH independent way of penetration?

A

virus goes straight through the cell wall

18
Q

What is the PH dependent method of penetration?

A

invagination (virus breaks down vacuole before reaching the phagosome)

19
Q

What are the two ways of release?

A

budding and lytic infection

20
Q

A virus has been formed and it has no envelope, in what way was it released?

A

lytic

21
Q

What is pantropism?

A

Influenza is a pantropic virus as its receptors are very common

22
Q

What are the 4 nucleoproteins of viruses?

A

Basically, don’t get your fingers or your helix trapped in your zipper!

Basic proteins
Finger proteins
Helix proteins
Zipper proteins