Inheritance quiz

Question 1

achondroplasia (FGF-R 3)

Answer 1

AD

Question 2

adult PKD (APKD1, chromosome 16)

Answer 2

AD

Question 3

albinism

Answer 3

AR

Question 4

Bruton’s agammaglobinemia

Answer 4

XLR

Question 5

cystic fibrosis

Answer 5

AR

Question 6

Duchenne (and Becker’s)

Answer 6

XLR

Question 7

Fabry’s

Answer 7

XLR

Question 8

familial adenomatous polyposis (APC gene, chromosome 5)

Answer 8

AD

Question 9

familial hypercholesterolemia (LDL-R)

Answer 9

AD

Question 10

fragile x

Answer 10

CGG repeats

Question 11

Friedrich’s ataxia

Answer 11

AR (GAA repeats, chromosome 9)

Question 12

G6PD deficiency

Answer 12

XLR

Question 13

glycogen storage diseases

Answer 13

AR

Question 14

hemochromatosis

Answer 14

AR

Question 15

Hemophilia A and B

Answer 15

XLR

Question 16

hereditary hemorrhagic telangiectasias = Osler-Weber-Rendu syndrome

Answer 16

AD

Question 17

hereditary spherocytosis (spectrin or ankyrin)

Answer 17

AD

Question 18

Hunter’s syndrome

Answer 18

XLR

Question 19

Huntington (chromosome 4)

Answer 19

AD

Question 20

infantile PKD

Answer 20

AR

Question 21

Lesch-Nyhan syndrome

Answer 21

XLR

Question 22

Marfan’s

Answer 22

AD

Question 23

MEN

Answer 23

AD

Question 24

mucopolysaccharidoses (except Hunter’s)

Answer 24

AR

Question 25

myotonic dystophy

Answer 25

CTG repeats

Question 26

NF-1 = von Ricklinghausen’s disease (q17)

Answer 26

AD

Question 27

NF-2 (chromosome 22)

Answer 27

AD

Question 28

ocular albinism

Answer 28

XLR

Question 29

PKU

Answer 29

AR

Question 30

sickle cell

Answer 30

AR

Question 31

sphingolipidoses (except Fabry’s)

Answer 31

AR

Question 32

thalassemias

Answer 32

AR

Question 33

Tuberous sclerosis

Answer 33

AD

Question 34

von Hippel-Lindau (VHL tumor suppressor gene, chromosome 3)

Answer 34

AD

Question 35

Wiscott-Aldrich syndrome

Answer 35

XLR