1.1

Question 1

principle of catabolism

Answer 1

reduced molecules -> oxidised molecule + energy

Question 2

amphibolic reaction

Answer 2

reversible, catabolic and anabolic reactions

Question 3

high energy p bond: used for, how is it made

Answer 3

metabolic energy stored via formation of high energy bond

phosphoanhydride bond; made by splitting H2O btw 2 phosphate

Question 4

why high energy?

Answer 4

large free energy charge (deltaG) of hydrolysis: NOT due to high bond energy, but due to free energy of hydrolysos

Question 5

energy of: ATP + H2O -> ADP or AMP

Answer 5

to ADP: delta G= 30.6kJ

to AMP: delta G= 31kJ

Question 6

function of AMP vs ATP

Answer 6

ATP: E- source used in energyrequiring, non-spontanious reaction

AMP: E-sensor and regulator of metabolism: stim metabolic pathways to make ATP if low conc

Question 7

synthesis of creatinine: where

Answer 7

1st in kidney
2nd in liver
3rd non-reversible in muscle

Question 8

creatine is used where

Answer 8

nerve and muscle cells: storage of P bonds

Question 9

creatine reaction

Answer 9

phosphocreatine + ADP -> creatine + ATP

creatine kinase

Question 10

thioester bond

Answer 10

-HSCoA

btw -COOH and thiol group

Question 11

thiol group can react with

Answer 11

acetic acid -> AcCoA

FA -> Fatty acyl-CoA

Question 12

what is essential to for the CoA role

Answer 12

the spontanity (exergonic) of thioester cleavage is essential as an acyl group carrier

Question 13

phosphocreatine energy prod

Answer 13

-43.1kJ/mol

Question 14

thioester energy prod

Answer 14

-31.48kJ/mol