Path: Infections Flashcards

0
Q

3 most common causes of bacterial neonatal meningitis.

A
  1. Strep agalactiae
  2. E. coli
  3. Listeria m.
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1
Q

Group of diseases that cause congenital conditions if a fetus is exposed to them in the uterus.

A
TORCH
Toxoplasmosis
Other (HIV, syphilis, varicella, mumps, parvovirus)
Rubella
CMV
Herpes Simplex
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2
Q

Most common bacterial causes of meningitis in adults.

A

Neisseria meningitidis

Strep pneumo

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3
Q

Complication from meningococcal meningitis.

A

Waterhouse-Fridereichsen syndrome

-adrenal hemorrhage

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4
Q

What is the difference in the WBC count between bacterial vs. viral meningitis?

A

Bacterial: increased PMNs

Viral: increased T cells (CD8)

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5
Q

Very common finding that is diagnostic of a brain abscess caused by Toxoplasmosis on CT scan.

A

Ring Enhanced Lesion

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6
Q

How does a TB meningitis lead to hydrocephalus?

A

TB causes chronic meningitis which leads to scarring of the arachnoid granulations and prevent CSF reabsorption.

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7
Q

Condition caused by neurosyphilis.

A

Tabes Dorsalis

-posterior column and dorsal root disease

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8
Q

What structures are affected by HSV-1 encephalitis that lead to memory and mood change?

A

Memory: temporal lobe
Mood: frontal lobe

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9
Q

Owl Eyes

A

Histologic characteristic of CMV infection. Most commonly affects AIDS pateints.

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10
Q

Major cause of death from a rabies infection.

A

It is an ascending infection and causes death by respiratory failure.

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11
Q

Name the virus and cell type that it infects in Progressive Multifocal Leukoencephalopathy.

A

JC polyomavirus

-infects oligodendrocytes

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12
Q

What infectious agent leads to Subacute Sclerosing Panencephalitis and what is the mechanism of tissue destruction?

A

Infection with measles virus that doesn’t get cleared from a primary infection and becomes altered.

-demyelinating disease

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13
Q

Main fungal infection in AIDS patients.

A

Cryptococcus neoformans

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