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Flash Card > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

CYP 450 inhibitors

Q got SICK and went to the GRAVE

A

Sulfonamides
Isoniazid
Cimetidine
Ketoconazole

Grapefruit Juice
Ritonavir
Amiodarone
Valproic Acid
Erythromycin
Quinidine
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2
Q

Antidotes of increase organophosphate

A

Atropine and pralidoxime

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3
Q

Antidotes of increase sympathomimetics

A

Phentolanine

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4
Q

Bacteriostatic

Bacteriosta TTEECCS

A 
Tetracycline 
Trimethoprim 
Erythromycin
Ethambutol
Clindamycin
Chloramphenicol
Sulfamethoxazole
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5
Q

Bactericidal

nag VF C PAM noong nag suicide

A 
Vancomycin
Fluoroquinolones 
Cephalosporins
Penicillins
Aminoglycoside 
Metronidazole
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6
Q

Chemo drugs side effects

Cisplatin and carboplatin

A

Ototoxic and Nephrotoxic

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7
Q

Chemo drugs side effects

Vincristine

A

Peripheral Neuropathy

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8
Q

Chemo drugs side effects

Busulfan and bleomycin

A

Pulmonary fibrosis

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9
Q

Chemo drugs side effects

Doxorubicin

A

Dilated cardiomyopathy

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10
Q

Chemo drugs side effects

Cyclophosphamide

A

Hemorrhagic cystitis

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11
Q

Chemo drugs side effects

5FU
6MP
Methotrexate

A

Bone marrow suppression

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12
Q

Chemo drugs side effects

Interferon A

A

Thyroid dysfunction

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13
Q

Chemo drugs side effects

Asparaginase

A

Acute pancreatitis

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14
Q

Samter triad of aspirin hypersensitivity

A

Asthma
Aspirin sensitivity
Nasal Polyps

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15
Q

Inhibitors of micro tubules assembly

Very Good CAT

A 
Vinca alkaloids
Griseofulvin
Colchicine
Azoles
Taxanes
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16
Q

Drugs used in lethal injection

Pota Patay THIO

A

Potassium Chloride 100 mEq
Pancuromium 100mg
Thiopental 5g

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17
Q

Date rape drugs

A

Alcohol
Flunitrazepam
Y hydroxybutyrate

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18
Q

Drugs that cause Livedo Reticularis

A 
Quinidine
Gemcitadine
Hydroxyurea
Amantadine
Minocycline
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19
Q

Zero order elimination (Michaelis-Menten Kinetics)

Rate of elimination is constant regardless of concentration

WHAT PET

A

Warfarin
Heparin
Aspirin
Tolbutamide

Phenytoin
Ethanol
Theophylline

20
Q

Drugs that display Tachyphylaxis

MEDical students Love to watch CNN on HD

A 
Metoclopramide
Ephedrine
Doubtamine
LSD
Calciton
Nitrogycerin
Nicotine
Hydralazine
Desmopressin
21
Q

High Anion Gap Metabolic Acidosis
AG> 12

MUDPILES

A 
Methanol
Uremia
Diabetic Ketoacidosis
Propylene Glycol
Iron/isoniazid
Lactic acidosis
Ethylene Glycol
Salicylates
22
Q

Normal anion GAP Metabolic Acidosis
AG <12

HARD ASS

A 
Hyperalimentation
Addison disease
Renal Tubular Acidosis
Diarrhea
Acetazolamide
Spirinolactone
Saline Infusion
23
Q

Maybe caused by nitrosylation of RYR 1 or halothane/succinylcholine

FARTCH

A

Malignant hyperthermia

24
Q

Malignant hyperthermia

Manifestations

A 
Fever
Acidosis
Rhabdomyolysis
Trismus
Clonus
Hypertension
25
Q

Malignant hyperthermia

Treatment

A

Dantroline

26
Q

Serotonin Syndrome

FAT CHD

A 
Fever
Agitation
Tremor
Clonus
Hyperrerlexia 
Diaphoresis
27
Q

Treatment for serotònin syndrome

A

Supportive

28
Q

Neuroleptic malignant syndrome

FEVER

A 
Fever
Encephalopathy
Vitals unstable
Elevated CPK
Rigidity
29
Q

Treatment for neuroleptic malignant syndrome

A

Diphenhydramine

30
Q

Drug induced Lupus

HIPP

A

Hydralazine
Isoniazid
Procainamide
Penicillamine

31
Q

Drugs that undergo acetylation

A

Hydralazine
Isoniazid
Procainamide
Sulfonamides

32
Q

Narrow Therapeutic Index

WALA C PaPa V DiTo

A 
Warfarin
Aminoglycoside 
Lithium
Amphotericin B
Carbamazepine
Phenobarbital
Phenytoin
Vancomycin
Digoxin
Theophylline
33
Q

Anti seizures

GABA mediated

BP-VTV

A 
Benzodiazepines (diazepam, clonazepam, lorazepam)
Phenobarbital
Valproic acid
Tiagabine
Vigabatrine
34
Q

Anti seizures

Decrease Na conductance

PCOLZ

A 
Phenytoin
Carbazepine
Oxcarbazepine 
Lamotrigine
Zonisamide
35
Q

Anti seizures

Decrease Ca current

A

Pregabalin
Ethosuximide
Gabapentin

36
Q

Anti seizures

INH excitatory

A

Felbimate

Topiramate

37
Q

Anti seizures

Modifies Glutamate and GABA receptors

A

Levetiracetam - not metabolized by CYP 450

38
Q

Anti seizures. CYP 450 inducers

A

Phenytoin
Carbazepine
Benzodiazepines

39
Q

Anti seizures

DOC of bipolar affective disease

A

Valproic Acid (for mania)

40
Q

Anti seizures

DOC of trigeminal neuralgia

A

Carbamazepine

41
Q

Anti seizures

DOC of neuropathic

A

Gabapentin

Pregabalin

42
Q

DOC of GTC

A

Valproic acid
Phenytoin
Carbamazepine

43
Q

DOC of partial seizures

A

Lamotrigine
Phenytoin
Carbamazepine

44
Q

DOC of absence seizure

A 
Ethosuximide (uncomplicated)
Valproic acid (complicated)
45
Q

DOC of myoclonic seizure

A

Valproic acid

46
Q

DOC of status Epilepticus

A

Lorazepam
Diazepam
Phenytoin
Phenobarbital

47
Q

CYP 450 inducers

Ethel and Barbie takes Phen-Phen and Refuses Greasy Carb Shakes

A 
Ethanol
Barbiturates
Phenytoin
Rifampicin
Gristofulvin
Carbamazepine
St. John's Wort/Smoking

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