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Flash Card > Biochem > Flashcards

Biochem Flashcards

1
Q

Pentose phosphate pathway or HMP shunt

Phase 2

A

Non oxidative reversible
Transketolase (required vit B1)

Ribose 5 P
GA 3 P
F 6 P

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2
Q

Pentose phosphate pathway or HMP shunt

Occurs in

A

Cytoplasm

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3
Q

Pentose phosphate pathway or HMP shunt

Used to diagnose thiamine deficiency

A

Transketolase

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4
Q

Pentose phosphate pathway or HMP shunt

For synthesis of nucleotides

A

Ribose 5 P

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5
Q

Pentose phosphate pathway or HMP shunt

Active in

A 
Liver
Adipose
Adrenals
Thyroid
Testes
RBC
Lactating mammaries
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6
Q

Pentose phosphate pathway or HMP shunt

Low in

A

Skeletal muscle

Non lactating mammaries

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7
Q

Glutathione

Components

A

Glutamyl
Cysteinyl
Glycine

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8
Q

Glutathione

Most important component that contain SH group

A

Cysteinyl

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9
Q

Lipoproteins

Chylomicrons

A

Intestine to tissues

APO B-48
APO C II
APO E

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10
Q

Lipoproteins

Chylomicrons that act lipoprotein lipase

A

APO C II

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11
Q

Lipoproteins

Chylomicrons uptake by livers

A

APO E

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12
Q

Lipoproteins

VLDL

A

Liver to tissue

APO B 100
APO C II
APO E

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13
Q

Lipoproteins

IDL

A

HDL to LDL

APO E

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14
Q

Lipoproteins

LDL

A

Delivers cholesterol to cells

APO B-100

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15
Q

Lipoproteins

HDL

A

Reverse cholesterol transport

APO A1 - activate LCAT

delivers cholesterol via SR- B1
Shuttles APO C II and APO E

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16
Q

Vitamin B12

Homocyteine to methionine

A

Methionine Sylthase

17
Q

Vitamin B12

Homocysteine to cystathionine

A

CBS - deficient in homocystinuria

18
Q

Vitamin B12

L - methymalonyl CoA to succinyl CoA

A

Methylmalonyl CoA mutase

19
Q

Vitamin B12

Not affected by folic acid def.. It means no neurologic symptoms in folic acid def!

A

L- methymalonyl CoA

20
Q

Folic Acid

PABA to dihydrofolic Acid

A

Dihydropteroate synthase

Sulfonamides

21
Q

Folic Acid

Dihydrofolic acid to tetrahydrofolic acid

A

Dihydrofolate reductase

Trimethoprim
MTX
Pyrimethamine

22
Q

Folic Acid

Pathways

A 
PABA
Dihydrofolic Acid
Tetrahydrofolic Acid
Purines
DNA
23
Q

Essential AA

PCT TIM HALL always Argue (arginine) never Tyres ( tyrosine)

A 
Phenylalanine
Valine
Tryptophan
Threonine
Isoleucine
Methionine
Histidine
Arginine
Leucine
Lysine
24
Q

Essential AA

All AA transfer amino group to Alpha KG except

A

Lysine

Threonine

25
Q

Pentose phosphate pathway or HMP shunt

Phase 1

A

Oxidative irreversible
G6PD

NADPH
Ribulose 5-p

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