POISONING Flashcards

1
Q

Delayed action

A

Aspirin, Iron, Paracetamol, TCA, Co-phenotrope

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2
Q

Hypertension

A

Cocaine, amphetamines, phencyclidine

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3
Q

Arrhythmia

A

TCA, Antipsychotics, Antihistamines

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4
Q

Hypothermia

A

Barbiurates, Antipsychotics, TCA

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5
Q

Hyperthermia

A

CNS stimulants, antimuscarinics, SSRI

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6
Q

Convulsions

A

Only treat if longer than 5 minutes - Lorazepam, Diazepam

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7
Q

Methaemoglobinaemia

A

Methylthioninium chloride

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8
Q

Activated charcoal - repeated doses, given by mouth

A

Carbamazepine, Dapsone, Phenobarbital, Quinine, Theophylline

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9
Q

Haemodialysis

A

Lithium, Salicylate, sodium valproate

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10
Q

Gastric lavage

A

Iron if life threatening

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11
Q

Alkalinising of urine

A

Give IV sodium bicarbonate to enhance urinary excretion

Salicylates

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12
Q

Alcohol symptoms

A

Ataxia, Dysarthria, Nystagmus, Drowsiness, Coma, Hypotension, Acidosis, Hypoglycaemia

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13
Q

Aspirin - concentration may not correlate to severity

A

Hyperventilation, Tinnitus, Deafness, Vasodilation, Sweating, Coma

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14
Q

Opioids

A

Coma, Respiratory depression, Pinpoint pupils

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15
Q

Opioid treatment

A

Naloxone - repeated injection may be needed

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16
Q

Buprenorphine

A

Only partially reversed

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17
Q

Methadone

A

Long duration of action so extended monitoring required

18
Q

Paracetamol maximal damage

A

3 to 5 days - right subcostal pain and tenderness

  • Hepatocellular necrosis
  • Renal tubular necrosis
  • Nausea and vomiting
19
Q

Paracetamol overdose complications

A

Encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema, death

20
Q

Acetylcysteine

A

Paracetamol - effective if infused within 24 hours

21
Q

Paracetamol monitoring

A

Plasma levels taken after 4 hours

3 consecutive IV infusion over a total of 21 hours

22
Q

TCA symptoms

A

Antimuscarinic , extensor plantar responses, hyperreflexia, hypothermia

23
Q

TCA treatment

A

Activated charcoal, IV lorazepam or Diazepam for convulsions, avoid antiarrhythmics

24
Q

SSRI symptoms

A

Nystagmus, Tachycardia, serotonin syndrome, rhabdomyolysis, hyperthermia

25
Q

Antipsychotic symptoms

A

Hypotension, hypothermia, tachycardia, dystonic reactions

26
Q

Antipsychotics treatment

A

Activated charcoal

27
Q

Treating dystonic reactions

A

Procyclidine injection or diazepam

28
Q

Benzodiazepines

A

Flumazenil

Give activated charcoal if mixed overdose with TCA or dependent patients

29
Q

Beta blockers treatment

A

Atropine sulfate

30
Q

Calcium channel blocker treatment

A

Hyperglycaemia - insulin
Activated charcoal
Calcium chloride or gluconate injection

31
Q

Iron treatment

A

Desferrioxamine mesilate

32
Q

Theophylline symptoms

A

Hyperglycaemia, dilated pupils, hypokalaemia, convulsions, nausea and vomiting

33
Q

Cyanide treatment

A

Oxygen, Dicobalt edetate, sodium thiosulfate, hydroxycobalamin

34
Q

Hypoglycaemia

A

Paracetamol, Alcohol

35
Q

Hyperglycaemia

A

Calcium channel blockers

36
Q

Hypotension

A

Antipsychotics, alcohol

37
Q

Dilated pupils

A

Calcium channel blockers, theophylline

38
Q

Hyperventilation

A

Aspirin

39
Q

Deafness and tinnitus

A

Aspirin

40
Q

Extensor planar + hyperreflexia

A

TCA