8/3 Flashcards

1
Q

What does a large rise in urea compared to creatine suggest?

A

Pre-renal cause of AKI

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2
Q

What are the causes of acute food poisoning?

A

ABC

staph Aureus
Bacillus cereus
Clostridium perfringens

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3
Q

What is the management of acute cholecystitis?

A

IV fluids an abx with analgesia

AND

within 1wk - laparoscopic cholecystectomy

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4
Q

If DKA has not resolved within 24hrs - what do you do next?

A

Senior endocrine review

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5
Q

Addison’s disease is managed with both hydrocortisone and fludrocortisone - what are they both?

What would you change if someone became ill?

A

Hydrocortisone = steroid - replace cortisol

Fludrocortisone = mineralocorticoid replacement - replace aldosterone

Steroids need doubled during sick day rules but fludro can stay the same

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6
Q

What are the cut-offs for gestational diabetes?

How is it managed?

A

5,6,7,8

Fasting => 5.6
2-hour => 7.8

  1. Diet and exercise ( fasting <7)
  2. Metformin (fasting >7)
  3. can add insulin

Pre-existing - only metformin and insulin can be used
- TREAT retinopathy can worsen during pregnancy - important to scan
- 5mg folic acid
- weight loss BMI >27

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7
Q

Reflex acronym

A

S1-2 - buckle my shoe (achilles)
L3-4 - kick the door (patellar)
C5-6 - pick up sticks (biceps)
C7-8, lay them straight (triceps)

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8
Q

What symptoms would necessitate a urine sample for women?

A

> 65
pregnant
haematuria (visible or non-visible)
atypical symptoms
catheter
recurrent UTI (2 in 6 months, 3 in 12 months)
persistent symptoms not responding to abx

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9
Q

What is the SSRI of choice in children?

A

Fluoxetine

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10
Q

UC vs Crohns

How is each managed?

What test can be done to exclude IBS and rule it in before colonscopy?

A

UC - Close UP

Continous inflam
Limited to rectum and colon
Only superfical mucosa
Smoking is protective
Excert blood and mucus

Use aminosalicylates (mesalazine) - topical (up the bum - won’t work if inflammation is too far away from rectum) or oral
PSC/psuedopolyps

Crohns - NESTS

No blood
Entire GI tract
Skip lesions
Transmural inflam/terminal ileum
Smoking (increases)/ Strictures

UC
1. mesalazine
2. flare-ups = steroids
- start with IV in hospital and then wean off to oral
3. curative = surgery

crohn’s
- steroids in flare-ups
- azathioprine in remission

Faceal calprotectin can rule out IBS

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11
Q

What should be prescribed if pt on SSRI and NSAID?

A

PPI - increases GI bleeding risk

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12
Q

Oral vancomycin not worked for C.diff - what’s next?

A
  1. Oral vancomycin
  2. Fidaxomicin (recurrent episode within 12 weeks go straight to this)
  3. Oral vancomycin + IV metronidazole (if life-treatening straight to this)
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13
Q

Inguinal vs femoral hernia

Indirect vs direct hernia

What can go wrong? When is it an emergency and need immediate surgical intervention?

A

Inguinal - superior and medial to pubic tubercule - through the superficial ring of inguinal canal

Femoral - inferior and lateral to pubic tubercule - through the femoral canal found medial in the femoral triangle (NAVY-C)

Indirect - through the superficial ring
- REDUCIBLE if press over deep ring

Direct - straight through the Abdo wall in hesselbach’s triangle
- NOT REDUCIBLE if press over deep ring (1/2 between ASIS and pubic tubercule)

Bowel can get caught outside and not be reducible and get ischaemic (very very painful with vomiting) - surgical emergency

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14
Q

Most common cause of traveller’s diarrhoea?

A

E.coli

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15
Q

How does a hiatus hernia present?

How is it managed?

What is most sensitive invx?

What are the two types

A

Chest pain
Dyspesia
Heartburn
regurg

Barium swallow (most found on endoscopy)

Medically for most - PPIs
If symptomatic ~surgery

Sliding (GOJ above diaphragm) - 95%

Rolling (GOJ remains below but other part of stomach has come up) - 5%

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16
Q

What forms Hesselbach’s triangle?

A

Medial - rectus abdominus
Superior - inguinal vessels
Inferior - inguinal ligamament

17
Q

Signs of compensated cirrhosis vs decompensated cirrhosis

How is ascites managed?

What are you at increased of following TIPPS?

A

Compensated
- palmar erythema
- spider naevi
- gynaecomastia
(all above are due to impaired oestrogen metabolism -> increased oestrogen)

Decompensated
- ascietes
- encephalopathy
- variceal bleed
- jaundice

TIPPS - increased risk of encephalopathy as shunting over the liver and ammonia no longer being metabolised

Ascites managed
- spironolactone
- fluid restriction
- TIPPS

18
Q

When ascites is established a tap should be done followed by a SAAG. What is this? What does it tell us?

A

serum albumin ascites gradient
helps to establish cause of ascietes

/think about in similar way to pleural effusion/

high gradient (small amount of albumin in tap compared to serum = high pressure causes)
- heart failure
- cirrhosis/liver failure
- budd chiari syndrom e
- constrictive pericarditis

low gradient (levels of albumin similar in tap and serum = leaky vessel causes)
- cancer of peritoneum
- nephrotic syndrome
- TB
- pancreatitis

19
Q

What type of IBD is associated with toxic megacolon?

A

UC

Colon >5cm
Loss of hastrua (not how its spelt)

20
Q

What is 1st line invx for pancreatic cancer?

A

CT abdo