8: Alcohol use disorders Flashcards Preview

Psychiatry Week 1 2018/19 > 8: Alcohol use disorders > Flashcards

Flashcards in 8: Alcohol use disorders Deck (28)
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1

Which percentage of the population drink half of all alcohol consumed in the UK?

10%

2

Which groups of the population have the highest rates of drinking?

Adolescents

20 - 30

3

What is a unit of alcohol?

10ml of pure alcohol

4

What is a high risk drinker?

Someone who consumes > 14 units of alcohol per week

5

What are the UK guidelines for alcohol consumption?

< 14 units per week

Ideally spread throughout the week

With at least three drink-free days

6

The harm caused by excessive alcohol consumption may be ___, ___ or ___.

physical

mental

social

7

As alcohol is an ___ drug, you can become ___ on it.

addictive

dependent

8

According to the ICD-10, what are some signs of dependence on an addictive drug?

Strong desire to take drug

Difficulty stopping once you've started

Persistent use despite evidence of harm (physical, psychological, social)

Neglect of other interests

Development of tolerance

Physiological withdrawal state if abstinent

9

Which tools can be used to detect harmful drinking in a patient?

AUDIT questionnaire

CAGE questionnaire - cut down, annoyed, guilty, eye-opener

10

Which tool is most commonly used in Scotland to detect harmful drinking?

AUDIT

11

In alcoholic liver disease, which liver enzymes may be raised?

ALT

AST

GGT

(AST > ALT because you're wASTed)

12

How can you raise the issue of harmful alcohol consumption in a consultation?

Brief intervention

same as with smoking

13

Which tool is used to measure a patient's alcohol dependence

SADQ

severity of alcohol dependence questionnaire

14

The greater your AUDIT and SADQ scores, the greater the ___ you need.

intervention

15

What are specialist interventions for alcohol dependence?

Detoxification

Relapse prevention

16

Alcohol is a (stimulant / depressant).

depressant

17

Which receptor does alcohol inhibit?

NMDA-glutamate (excitatory receptor, remember alcohol is a depressant)

18

Which receptor does alcohol stimulate?

GABA (inhibitory receptor)

19

Which receptors are

a) downregulated

b) upregulated

in chronic alcoholism?

a) Inhibitory receptors are downregulated due to overstimulation

b) Excitatory receptors are upregulated due to inhibition, leading to anxiety, dysphoria and seizures

20

What happens to dependent patients who don't consume alcohol?

Withdrawal

21

What are some physical symptoms of acute alcohol withdrawal?

Tremor

Sweating

Nausea

Visual hallucinations

Seizures

22

What occurs within 3 - 5 days of alcohol withdrawal syndrome?

Delirium tremens

Seizures, may be fatal

23

How is alcohol withdrawal syndrome managed?

Benzodiazepines (diazepam, chlordiazepoxide)

Vitamin supplementation (e.g thiamine; vit b1 to prevent encephalopathy)

24

Which vitamin deficiency can present in alcoholism?

Vitamin B1

25

Which neuro problems are caused by

a) acute

b) chronic

thiamine deficiency?

a) Wernicke's encephalopathy (reversible)

b) Korsakoff syndrome (irreversible)

26

What is the name of the Vitamin B1 supplement given to alcohol withdrawal patients?

Pabrinex

27

What is disulfiram?

Acetaldehyde dehydrogenase inhibitor

Makes patients feel crap when they drink alcohol (flushing, nausea)

28

What drugs, given for alcohol misuse disorders, reduce

a) alcohol cravings

b) alcohol's rewarding effects?

a) Naltrexone - craviNgs

b) Acamprosate - rewArd