Urinary system 1 Flashcards

1
Q

What are the main structures of the kidney?

A

Retroperitoneal
Renal capsule- tough fibrous layer covers kidney
Renal fascia-connective tissue, covers kidneys as well as adrenal glands
Hilum- recessed portion of kidneys, closest to midline, where vessels merge and ureter passes

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2
Q

What are the three types of nephrons?

A

cortical nephrons
midcortical nephrons
juxtamedullar nephrons

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3
Q

What three parts make up the glomerular filtration membrane?

A

Inner capillary endothelium-most internal and has large pores certain proteins and fluids can pass blood cells cant
Basement membraneprevent plasma proteins from being filtered out of bloodstream
Outer capillary epithelium-wrap around capillaries with spaces, create framework where filtration can occur.

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4
Q

What two parts make up the Juxtaglomerular apparatus?

A

Juxtaglomerular cells-Renin releasing

Macula densa-Sodium sensing

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5
Q

What are the three main urinary structures

A

ureter, bladder and uretha

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6
Q

What is glomerular filtration rate?

A

Filtration of the plasma per unit of time

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7
Q

How is neural regulation involved with renal blood flow

A

Sympathetic fibres regulate size of afferent and efferent arterioles, thus renal blood flow
No significant parasympathetic regulation

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8
Q

What hormones are involved with renal blood flow?

A

Renin-angiotensin-aldosterone system
Natriuretic peptides
Urodilantin

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9
Q

What is the function of the nephron?

A
Filters plasma
Reabsorbs and secretes
Tubular reabsorption and secretion
Forms a filtrate of protein-free fluid
Regulates the filtrate to maintain fluid volume, electrolytes, and pH
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10
Q

what occurs at the Loop of Henle and distal tubule

A

Concentration or dilution of urine

Countercurrent exchange system

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11
Q

What occurs at the proximal convoluted tubule?

A

Active reabsorption of sodium

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12
Q

What is glomerulotubular balance?

A

Adjustment of reabsorption of sodium and water

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13
Q

what is the countercurrent exchange system?

A

Contributes to production of concentrated urine
Fluid flows in opposite direction through parallel tubes
Fluid moves up and down the parallel limbs of the loop of Henle
The longer the loop, the greater the concentration gradient

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14
Q

What is vitamin D essential for?

A

Necessary for the absorption of calcium and phosphate

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15
Q

What is Erythopotein used for?

A

Released when decreased oxygen to the kidney

Stimulates RBC production

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16
Q

What are some tests for renal blood flow?

A

=Clearance and renal blood flow
=Clearance and glomerular filtration rate-Inulin-Cystatin C-Creatinine
=Blood tests-Plasma creatinine concentration-Blood urea nitrogen (BUN)
=Urinalysis

17
Q

What happens to renal function as you age?

A

=Decrease in renal blood flow and GFR-Altered sodium and water balance
=Number of nephrons decrease due to renal vascular and perfusion changes-Response to acid–base changes delayed
=Increased risk for medication toxicity
=Alterations in thirst and water intake