Obstetrics, gynaecology and urinary-tract disorders- MoA

Question 1

Desogestrel and ethinyl-estradiol

Etonogestrel

Answer 1

Mimics ovulation, reduces LH and FSH

Question 2

Hormone replacement therapy (HRT)

Answer 2

Restores decreased hormone level and function

Question 3

Dinoprostone

Answer 3

Prostaglandin E2- stimulates cervical ripening

Question 4

Oxytocin

Answer 4

Stimulation of uterine contraction

Question 5

Mifepristone with Misoprostol

Answer 5

Steroidal antiprogestogen in combination with synthetic prostaglandin

Question 6

Tranexamic acid

Answer 6

Inhibits fibrin clot breakdown by plasmin

Question 7

Mefenamic acid

Answer 7

Inhibition of prostaglandin synthesis

Question 8

Tamsulosin

Answer 8

Smooth muscle relaxant acting on bladder neck

Question 9

Urinary antispasmodics (antimuscarinic)

Answer 9

Blockade of acetylcholine receptors leading to bladder smooth muscle relaxation

Question 10

Mirabegron

Answer 10

Stimulation of Beta-3 adrenergic receptors, leading to detrusor smooth muscle relaxation

Question 11

Finasteride

Answer 11

Inhibition of synthesis of dihydrotestosterone

Question 12

Oral combination pill contraceptives

Answer 12

Suppresses ovulation, reduces LH and FSH

Question 13

Oral mini-pill contraceptives

Answer 13

Suppresses ovulation, reduces LH and FSH

Endometrial change, thickening of cervical mucus

Question 14

Ulipristal

Answer 14

Stimulation of progesterone-like responses in pituitary and endometrium