Anaesthetics - MoA Flashcards

1
Q

Propofol, isoflurane, sevoflurane

A

Possible enhancement of GABA function

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2
Q

Ketamine

A

NMDA receptor blockade

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3
Q

Local anaesthetics

A

Voltage-gated sodium channel blockade

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4
Q

Atracurium besilate, vecuronium

A

Competitive antagonist at AChR

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5
Q

Suxamethonium

A

Initially depolarisation and desensitisation AChR

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6
Q

Sugammadex

A

Oligosaccharide that forms a complex with Vecuronium & Rocuronium removing them from NMJ
Oligosaccharide that forms a complex with NMBs

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7
Q

Neostigmine

A

Peripheral acetylcholinesterase inhibitor

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8
Q

Dexmedetomidine

A

Alpha-2 agonists inhibit sympathetic activity

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9
Q

Cyclizine

A

Histamine H1 receptor blockade

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10
Q

Domperidone

A

Dopamine D2 receptor blockade in the chemoreceptor trigger zone

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11
Q

Neuromuscular blockers

A

Acetylcholine blockade

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