LABA

Question 1

LABA mechanism of action

Answer 1

increase cAMP

Question 2

What does an increase of cAMP cause?

Answer 2

Bronchial smooth muscle relaxation and inhibit hypersensitivity mediators from mast cells (histamine and leukotrienes)

Question 3

Arformoterol tartrate brand name and dosage form

Answer 3

Brovana Nebulizer solution

Question 4

Arformoterol tartrate age range

Answer 4

Adult

Question 5

Formoterol brand name dosage form

Answer 5

Perforomist nebulizer solution

Question 6

Formoterol age range

Answer 6

Adult

Question 7

Indacaterol brand name and dosage form

Answer 7

Arcapta Neohaler

Question 8

Indacaterol age range

Answer 8

Adult

Question 9

Olodaterol brand name

Answer 9

Striverdi Respimat

Question 10

Olodaterol age range

Answer 10

Adult

Question 11

Salmeterol age range

Answer 11

5 and up

Question 12

LABA adverse effects and clinical pearls (70

Answer 12

AE: tachycardia, headache, tremor, hypoalemia
Boxed warning for increased risk of asthma related death for all monotherapy LABA use- should not be used alone asthma management
Boxed warning for increasing hospitalizations in pediatric and adolescent patients
Prolonged QT seen with intentional overdoses
Not for acute symptoms
May be helpful for exercise induce bronchospasm
Formoterol and indacaterol capsules should not be taken orally

Question 13

Salmeterol brand name and dosage form

Answer 13

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