Bone Healing

Question 1

Wolff’s Law

Answer 1

Bone undergoes modeling and remodeling in response to forces acting on it

Question 2

Osteogenesis

Answer 2

Process of bone development or repair (phases)

Question 3

Osteoid Production

Answer 3

Step 1 of Osteogenesis
Create of colleagues matrix or organic framework
Stem cells produce osteoblasts to create osteoid
Some osteoblasts stay on external (periosteum) and internal (endosteum)

Question 4

Mineralization

Answer 4

Step 2 of osteogenesis

Osteoblasts assemble calcium and phosphate ions to form salts then hydroxyapatite (HA) to deposit around matrix

Question 5

Remodeling

Answer 5

Either resorption of unused bone or damage, stimulation and new bone formation

Question 6

Graft or Fracture Healing

Answer 6

1. Hematoma and Inflamation
2. Granulation tissue results as debris creates osteoblasts
3. Soft Callus; initial stages of mineralization
4. Calcification
5. Remodeling

Question 7

Intercortical Bridging

Answer 7

Gap is rigidly fixed and union occurs between structures

Question 8

Extena Callus Bridging

Answer 8

New bone grows from periosteum surrounding site and stimulate callus formation

Question 9

Intramedullary Bridging

Answer 9

Callus arises from Endsteum