Endocrine Flashcards

1
Q

Adrenals

A

Middle- Medulla - catecholamines, stimulates by splanchnic nerves releasing ach

Reticularis- sex hormones - ach from pituitary
Fasciculata- cortisol - stress, causes opposites effects insulin, reduces immune system
Glomerulosa- aldosterone thay acts on DCT, stimulates by high potassium or angiotensin

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2
Q

Adrenal embryology

A

Cortex mesoderm

Medulla ectoderm

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3
Q

Pellagra

A

B3

Dermatitis, dementia, diarrhoea

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4
Q

Carcinoid tumour

A

Serotonin secreting, often Bowels
Urinary 5HHA

Surgery for appendix
>2cm
Base 
Mesoaplendix 
Periappendical fat
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5
Q

Ebv cancers

A

Nasopharyngeal
Burkitts lymphomas
Hodgkins lymphomas

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6
Q

Kapsosis sarcoma

A

A

HSV 8

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7
Q

Has humorous and cancer

A

Lymphoma

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8
Q

Thyroid cancer

A

Medullary and papillary - spread lymp
Follicular - blood spread, orphan Annie

Papillary - previous radiation spreads both sides

Medullary needs bilateral neck dissection others central

Lymphoma -= hashimotos and non hodgkins chemradio

Lugols treats thyortoxicosis from surgery

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9
Q

Low for pride

A

Overdose of insulin

High of insulinoma

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10
Q

Feltys syndrome

A

Neutropenia, ra, splenomegaly

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11
Q

High dose dex suppression test

A

Pit tumours

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12
Q

Congenital adrenal hyperplasia

A

21- testosterone
17 - aldosterone
11- both

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13
Q

Adrenal crisis

A

Hypotension no response vasopressors

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14
Q

Adrenal cancer

A

10% extra - aorta organ of zuckercan
10 bilateral
10 kids1
10 MEN

Alpha blocker - phenoxtbenzaine

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15
Q

Nevrolytic migrans

A

Glucogonma

Depression
Diabetes

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16
Q

C- cells

A

Neural crest

4th pouch

17
Q

Inferior thyroid artery

A

Supply’s whole of parathyroid

18
Q

Thyroid cancer

A

Microcalcifications
Hypoechoic
Lymphatic infiltration
Irregular margins

19
Q

Papillary cancer

A

Radiation causes
LN spread
Central dissection if LN then level 6

20
Q

Follicular

A

Blood spread

If LN then modified radical neck dissection

21
Q

Medullary

A

Raised CEA
Parafollicular cella’s

Ret- men

If no nodes then central dissection
If nodes then added lateral dissection

22
Q

Parathyroid hormone

A

Osteoclasts
Kidneys

Vit d = bowels

Calcitonin = osteoclasts

23
Q

Most common location of ectopic thyroid

A

Thymus

Carotid sheath
Retro oesophagus

24
Q

High plasm ca

Low urinary ca

A

Familial hypercalceamia

No intervention