Autonomic Nervous System Part II: Adrenergic Antagonists Flashcards
What are the two main categories of adrenergic antagonists
alpha blockers and beta blockers
which receptors does phenoxybenzamine block
alpha 1 and alpha 2 receptors
what kind of cardiovascular effects does phenoxybenzamine have
decreased peripheral resistance, increased cardiac output
when is phenoxybenzamne used
if tumor present called pheochromcytom
What is an adverse effect of phenoxybenzamine
hypotension , nasal stiffness, inhibition of ejaculaition
describe what phentolamine blocks
alpha 1 and alpha 2
when is phentolamine given
used for short term management of pheochtmocytoma and treatment of hypertensive crisis
t/f phentolamine is a competivite inhibitor
true
what kind of receptor does prazosin target
selctive competitive blocker of alpha 1 receptors
why is prazosin used
- hypertension
2. benign prostatic hyperplasia
what are adverse effects of prazosin
dizziness , nasal congestion, orthostatic hypotension
What receptors does propranol block
beta 1 and beta 1
what is a special consideration that must be made for diabetic patients taking propranolol
it caues decreased glycogenolysis and glucagon secretion, therefore blood glucose must be carefully monitered
whats the general rule can be used for beta blockers
A-M = Block beta 1 M-Z = Block Beta and Beta 2
What are 5 uses for propranolol
- hypertension
- hypertension
- migranine
- hyperthyroidism
5 angina
6.MI
