Haematology Flashcards
1
Q
Define massive transfusion
A
replacement of >1 blood volume (av 20 units) in <24 hours
or >2 x circulating volume in paeds
Components PRBC, Plt, FFP
2
Q
What is the circulating volume of blood in neonates?
A
80-90ml/kg
3
Q
When would you transfuse PRBC?
A
- acute blood loss (15% TBV)
- asymptomatic but Hb <8
- Symptoms of anaemia at rest
- in neonates if preop Hb<15g/dl
4
Q
What antibodies would be present in type AB blood?
A
none - which is why they can take all other blood type donors
5
Q
Reversal agent for dabigatran?
A
praxbind (idarucizumab)
6
Q
When would you used FFP or PCC?
A
Emergency reversal of warfarin
7
Q
How does enoxaparin work?
A
Binds and accelerates function of antithrombin III. Inhibits thrombin and factor Xa
8
Q
How does aspirin work?
A
irreversible COX-1 inhibitor
