Pharmacology Flashcards

1
Q

What is the MOA of Penicillin?

A

Bactericidal via beta-lactam blocking peptidoglycan synthesis in bacterial cell wall

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2
Q

What are the ADR’s of Penicillin?

A

Angioedema, diarrhoea, fever, hypersensitivity reaction, joint pains, rashes, anaphylaxis

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3
Q

What are the CI’s of Penicillin?

A

Previously sensitive to beta-lactam antibiotics

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4
Q

What is the MOA of Ciproflaxacin?

A

Bacteriostatic via quinolone acting as tropoisomerase inhibitor = no bacterial DNA replication

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5
Q

What are the ADR’s of Ciproflaxacin?

A

Diarrhoea, dizziness, headaches, nausea, vomiting, achilles tendon rupture

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6
Q

What are the CI’s of Ciproflaxacin?

A

Previous sensitivity or tendon rupture

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7
Q

What is the MOA of Daptomycin?

A

Bactericidal by drug inserting into bacterial cell membrane -> ion pores = depolarise + kill bacteria

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8
Q

What are the ADR’s of Daptomycin?

A

Abd. pain, GI disturbances, anaemia, rash

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9
Q

What are the CI’s of Daptomycin?

A

Pregnant

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