Pharmacogenetics Flashcards
how do people respond to drug therapy related to their genetic makeup
pharmacogenetics
pharmacogenetics is the same as
pharmagonetics
study on how patient genomes affect drug response
pharmacogenetics
helps individualize optimal drug treatment regimens
pharmacogenetics
help decrease drug reactions
pharmacogenetics
promote drug regimen adherence
pharmacogenetics
reduces overall healthcare costs
pharmacogenetics
what patients benefit from pharmacogenetics?
- those taking multiple prescription drugs
- those not responding to current therapy
- those having adverse drug reactions
- those taking black box warning drugs
what is not available for every drug?
pharmacogenetic testing
treats leukemia
mercaptopurine
treat colon cancer, small lung cancer. want to eliminate if have genetic variation
irinotecan
treat HIV, 10% public has this and its life threatening effects
Abacavir
not used widely vitamin K is antagonist, anticoagulant, increases risk of bleeding
warfarin
codeine, tramadol (not given in active form). some people don’t have enzyme. 10% to convert this. some don’t have pain control (Asians and middle eastern)
opioids
antianalytic, nerve pain, increase immune response and can develop Steven Johnson syndrome
carbamazepine