14. Antiobiotics Flashcards

1
Q

inhibitors of transcription

A
  • rifampicin

* dactinomycin

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2
Q

•inhibitors of protein synthesis

A
  • streptomycin and aminoglycosides
  • tetracycline
  • chloramphenicol
  • clindamycin and macrolides
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3
Q

binds to ß subunit of DNA dependent RNA polymerase

A

rifampicin

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4
Q

binds to the DNA template and interfere with the movement of RNA polymerase during transcription

A

dactinomycin

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5
Q

binds with the 30S subunit and interferes with initiation

A

streptomycin and aminoglycosides

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6
Q

prevents bindng of amino-acyl tRNA to the A site

A

tetracycline

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7
Q

inhibits prokaryotic peptidyltransferase

A

chloramphenicol

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8
Q

binds to the 50S suunit and inhibits translocation

A

clindamycin and macrolides

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