96. Hepatic Vascular Anomalies Flashcards
(199 cards)
What is the primary function of the portal vein in the liver?
To supply 75% to 80% of the afferent blood volume and 50% of the oxygen supply to the liver.
Name two clinical signs associated with hepatic encephalopathy in dogs.
Seizures and ataxia.
What is the main blood vessel supplying oxygenated blood to the liver apart from the portal vein?
Hepatic artery.
What type of portosystemic shunt is most common in small or toy breed dogs?
Extrahepatic portosystemic shunt.
What congenital vascular anomaly is characterized by multiple arterial and venous communications within the liver?
Hepatic arteriovenous malformation.
Which vein in dogs typically divides into right and left branches 0.5 to 1.0 cm beyond its gastroduodenal tributary?
Portal vein.
What condition is characterized by small intrahepatic portal vessels and may be accompanied by fibrosis?
Primary hypoplasia of the portal vein without portal hypertension (previously known as microvascular dysplasia).
What is the major neurotoxic substance thought to play a role in hepatic encephalopathy?
Ammonia.
In dogs with congenital portosystemic shunt (PSS), which breed has the highest reported odds ratio for this condition?
Yorkshire Terrier.
Which dietary adjustment is recommended to manage hepatic encephalopathy in dogs with PSS?
Protein restriction with high-quality protein sources, such as milk or vegetable protein.
What imaging modality is considered the gold standard for evaluating the portal venous system in humans?
Computed tomographic angiography.
Name a condition that commonly presents with similar signs to hepatic vascular anomalies in small breed dogs.
Toy-breed hypoglycemia.
What is the purpose of bile acids in liver function tests for animals with PSS?
To evaluate liver function by measuring the liver’s ability to process and recirculate bile acids.
What breed is associated with intrahepatic portosystemic shunt (PSS) in large dogs?
Irish Wolfhound.
What enzyme’s activity is often measured to differentiate between PSS and portal vein hypoplasia without portal hypertension?
Protein C.
What is a common histologic finding in dogs with congenital PSS?
Bile duct proliferation and hypoplasia of intrahepatic portal tributaries.
Name one clinical sign specific to cats with congenital PSS.
Ptyalism (excessive salivation).
Which vein in the liver receives blood from the papillary process of the caudate lobe in dogs?
Left portal vein.
What imaging technique uses technetium for detection of portosystemic shunts?
Nuclear scintigraphy.
Name the blood test most commonly used to screen for liver dysfunction in animals with hepatic vascular anomalies.
Serum bile acids test.
What is the cause of microcytic anemia often seen in dogs with PSS?
Hypoferremia.
Which condition in dogs may present with signs of urolithiasis due to ammonium urate crystalluria?
Congenital portosystemic shunt.
What medical therapy is often used to reduce ammonia levels in hepatic encephalopathy?
Lactulose.
Name a coagulation disorder common in dogs with PSS.
Prolonged prothrombin time (PT).