Antidepressants (venlafaxine/mirtazapine)

Question 1

venlafaxine/mirtazapine indications

Answer 1

Major depression when SSRI not working, GAD (venlafaxine)

Question 2

Venlafaxine class

Answer 2

SNRI

Question 3

Mirtazapine class

Answer 3

pre-synaptic alpha adrenoceptors

Question 4

MOA for venlafaxine and mirtazapine

Answer 4

increase monoamines for neurotransmission

Question 5

When to stop venlafaxine/mirtazapine

Answer 5

6 months after depression stops, 2 years for recurrent depression

Question 6

When should consider changing dose/drug

Answer 6

4 weeks if no effect